Publication Name	World Journal of Hepatology
Manuscript ID	30650
Country	Brazil

Received	2016-10-11 08:34
Peer-Review Started	2016-10-12 19:41
To Make the First Decision	2016-12-13 15:49
Return for Revision	2016-12-14 10:38
Revised	2017-01-09 21:54
Second Decision	2017-01-18 11:12
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-02-13 13:51
Articles in Press	2017-02-13 13:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-03-08 10:48
Publish the Manuscript Online	2017-03-13 13:20

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Concordance of non-invasive mechanical and serum tests for liver fibrosis evaluation in chronic hepatitis C
Manuscript Source	Invited Manuscript
All Author List	Denise C Paranaguá-Vezozzo, Adriana Andrade, Daniel F C Mazo, Vinicius Nunes, Ana L Guedes, Taisa G Ragazzo, Renata Moutinho, Lucas S Nacif, Suzane K Ono, Venâncio A F Alves and Flair J Carrilho
Funding Agency and Grant Number
Corresponding Author	Daniel F C Mazo, MD, PhD, Division of Clinical Gastroenterology and Hepatology, Hospital das Clínicas, Department of Gastroenterology, University of São Paulo School of Medicine, Avenida Dr. Eneas Carvalho de Aguiar, 255, sala 9159, São Paulo 05403-900, Brazil. daniel.mazo@hc.fm.usp.br
Key Words	Elastography; Serum markers; Hepatitis C virus; Liver stiffness; Liver biopsy
Core Tip	Liver fibrosis evaluation in hepatitis C virus (HCV) patients has critical impact on prognosis and treatment strategies. Despite liver biopsy (LB) remains the gold standard for its evaluation, non invasive methods has improved in recent years. We evaluated 81 HCV patients with elastography methods [Fibroscan and acoustic radiation force impulse (ARFI)] and serum markers (APRI and FIB-4) compared to LB, and found that Fibroscan, ARFI, and FIB-4 independently identify advanced fibrosis. We suggest that FIB-4 alongside Fibroscan and ARFI may be good tools for the prediction of severity of liver fibrosis. This may be of particular importance to developing countries.
Publish Date	2017-03-13 13:20
Citation	Paranaguá-Vezozzo DC, Andrade A, Mazo DFC, Nunes V, Guedes AL, Ragazzo TG, Moutinho R, Nacif LS, Ono SK, Alves VAF, Carrilho FJ. Concordance of non-invasive mechanical and serum tests for liver fibrosis evaluation in chronic hepatitis C. World J Hepatol 2017; 9(8): 436-442
URL	http://www.wjgnet.com/1948-5182/full/v9/i8/436.htm
DOI	http://dx.doi.org/10.4254/wjh.v9.i8.436

Full Article (PDF)	WJH-9-436.pdf
Full Article (Word)	WJH-9-436.doc
Manuscript File	30650-Review.docx
Answering Reviewers	30650-Answering reviewers.pdf
Audio Core Tip	30650-Audio core tip.m4a
Biostatistics Review Certificate	30650-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	30650-Conflict-of-interest statement.pdf
Copyright License Agreement	30650-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	30650-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	30650-Language certificate.pdf
Peer-review Report	30650-Peer-review(s).pdf
Scientific Misconduct Check	30650-Scientific misconduct check.pdf
Scientific Editor Work List	30650-Scientific editor work list.pdf