Publication Name	World Journal of Gastroenterology
Manuscript ID	3072
Country	China

Received	2013-04-05 22:22
Peer-Review Started	2013-04-06 15:20
To Make the First Decision	2013-04-16 09:05
Return for Revision	2013-04-20 16:21
Revised	2013-05-05 19:51
Second Decision	2013-07-18 15:16
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-07-19 03:55
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-08-14 18:15
Typeset the Manuscript	2013-08-19 16:07
Publish the Manuscript Online	2013-09-26 18:39

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Transplantation
Manuscript Type	Minireviews
Article Title	Tolerance and chimerism and allogeneic bone marrow/stem cell transplantation in liver transplantation
Manuscript Source	Invited Manuscript
All Author List	Sheng-Li Wu and Cheng-En Pan
Funding Agency and Grant Number
Corresponding Author	Sheng-Li Wu, MD, PhD, Department of Hepatobiliary Surgery, First Affiliated Hospital of Xi'an Jiaotong University, No. 277, Yanta West Road, Xi'an 710061, Shaanxi Province, China. shengliyili@hotmail.com
Key Words	Immunotolerance; Chimerism; Bone marrow transplantation; Stem cell transplantation; Liver transplantation
Core Tip	The liver is considered an immune privileged organ. The main challenge facing liver transplantation is to induce donor-specific tolerance. Numerous reports have documented the phenomenon of microchimerism in liver transplant recipients. Most have demonstrated that higher levels of chimerism in liver transplantation are associated with reduced incidence of acute rejection and better initial graft acceptance. Mechanisms involved in chimerism-induced tolerance have only been partly elucidated. Chimerism can be induced through transplantation of allogeneic donor bone marrow cells under appropriate host conditioning and represents a clinically feasible approach for the induction of durable liver transplantation tolerance.
Publish Date	2013-09-26 18:39
Citation	Wu SL, Pan CE. Tolerance and chimerism and allogeneic bone marrow/stem cell transplantation in liver transplantation. World J Gastroenterol 2013; 19(36): 5981-5987
URL	http://www.wjgnet.com/1007-9327/full/v19/i36/5981.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i36.5981

Full Article (PDF)	WJG-19-5981.pdf
Manuscript File	3072-Review.doc
Answering Reviewers	3072-Answering reviewers.pdf
Copyright License Agreement	3072-Copyright assignment.doc
Non-Native Speakers of English Editing Certificate	3072-Language certificate.pdf
Peer-review Report	3072-Peer review(s).pdf
Scientific Editor Work List	3072-Scientific editor work list.doc