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Articles Published Processes
4/13/2017 3:45:15 PM | Browse: 1148 | Download: 1589
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Received |
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2016-10-19 10:35 |
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Peer-Review Started |
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2016-10-23 19:54 |
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To Make the First Decision |
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2016-12-19 08:47 |
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Return for Revision |
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2016-12-20 15:46 |
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Revised |
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2017-01-12 12:46 |
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Second Decision |
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2017-01-23 12:52 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-02-13 13:44 |
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Articles in Press |
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2017-02-13 13:44 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2017-03-19 06:52 |
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Typeset the Manuscript |
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2017-03-28 17:12 |
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Publish the Manuscript Online |
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2017-04-13 15:45 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Efficacy and safety of dual therapy with daclatasvir and asunaprevir in elderly patients
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Kazuo Tarao, Katsuaki Tanaka, Akito Nozaki, Akira Sato, Toshiya Ishii, Hirokazu Komatsu, Takaaki Ikeda, Tatsuji Komatsu, Shozo Matsushima and Kenji Oshige |
| Funding Agency and Grant Number |
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| Corresponding Author |
Kazuo Tarao, MD, Tarao’s Gastroenterological Clinic, Taiyo-Building, 2-58-6, Futamatagawa, Asahi-ku, Yokohama 241-0821, Japan. nrg18449@nifty.com |
| Key Words |
Asunaprevir; Chronic hepatitis; Daclatasvir; Dual oral therapy; Elderly patients; Hepatitis C virus infection; Hepatitis C virus; Liver cirrhosis |
| Core Tip |
Recently, it was demonstrated that dual oral therapy with daclatasvir and asunaprevir without pegylated-interferon/ribavirin was well tolerated and achieved high sustained virological response rates in Japanese patients with chronic hepatitis C virus genotype Ιb infection, including patients with liver cirrhosis (Child A stage). However, the efficacy and side effects of these drugs was previously studied in non-elderly patients (less than 70 years of age). Those in elderly patients, who are supposed to have higher incidence of hepatocellular carcinoma, have not been studied. We demonstrated that efficacy and side effects in elderly patients were nearly the same as in non-elderly patients. |
| Publish Date |
2017-04-13 15:45 |
| Citation |
Tarao K, Tanaka K, Nozaki A, Sato A, Ishii T, Komatsu H, Ikeda T, Komatsu T, Matsushima S, Oshige K. Efficacy and safety of dual therapy with daclatasvir and asunaprevir in elderly patients. World J Hepatol 2017; 9(11): 544-550 |
| URL |
http://www.wjgnet.com/1948-5182/full/v9/i11/544.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v9.i11.544 |
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