BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
3/9/2017 4:09:00 PM | Browse: 1096 | Download: 1984
 |
Received |
|
2016-10-27 21:22 |
|
Peer-Review Started |
|
2016-10-31 15:35 |
|
To Make the First Decision |
|
2016-12-01 14:31 |
|
Return for Revision |
|
2016-12-05 13:37 |
|
Revised |
|
2016-12-14 17:36 |
|
Second Decision |
|
2016-12-20 15:41 |
 |
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2017-01-03 15:37 |
|
Articles in Press |
|
2017-01-03 15:37 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2017-03-07 09:28 |
|
Publish the Manuscript Online |
|
2017-03-09 16:09 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Statin, testosterone and phosphodiesterase 5-inhibitor treatments and age related mortality in diabetes
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Geoffrey Hackett, Peter W Jones, Richard C Strange and Sudarshan Ramachandran |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Bayer plc to University of Bedfordshire |
BSP-SOP-040 |
|
| Corresponding Author |
Sudarshan Ramachandran, PhD, FRC Path, Professor, Department of Clinical Biochemistry, Heart of England NHS Foundation Trust, Good Hope Hospital, Rectory Road, Sutton Coldfield, West Midlands B75 7RR, United Kingdom. sud.ramachandran@heartofengland.nhs.uk |
| Key Words |
Type 2 diabetes; Mortality; Gompertz-Makeham equation; Phosphodiesterase 5 inhibitors; Male hypogonadism; Statins; Testosterone replacement therapy |
| Core Tip |
We have described a study of men with type 2 diabetes showing that mortality rates are in accordance with the pattern described nearly 200 years ago by Benjamin Gompertz. The data show that statin, phosphodiesterase 5 inhibitors (PDE5I) and testosterone replacement in hypogonadal men reduce all-cause mortality. PDE5I, alone and in combination with the other 2 agents alters the association between age and mortality, thus improving prognosis. The graphical illustrations adopted in this paper communicate the impact of medical intervention very effectively to patients and this could potentially improve compliance leading to significant clinical benefit. |
| Publish Date |
2017-03-09 16:09 |
| Citation |
Hackett G, Jones PW, Strange RC, Ramachandran S. Statin, testosterone and phosphodiesterase 5-inhibitor treatments and age related mortality in diabetes. World J Diabetes 2017; 8(3): 104-111 |
| URL |
http://www.wjgnet.com/1948-9358/full/v8/i3/104.htm |
| DOI |
http://dx.doi.org/10.4239/wjd.v8.i3.104 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
