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Articles Published Processes
5/12/2017 10:16:48 PM | Browse: 1135 | Download: 1825
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Received |
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2016-10-31 11:10 |
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Peer-Review Started |
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2016-11-03 17:20 |
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To Make the First Decision |
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2016-12-01 14:39 |
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Return for Revision |
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2016-12-07 08:31 |
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Revised |
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2016-12-20 16:14 |
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Second Decision |
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2017-01-18 11:15 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-02-13 13:54 |
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Articles in Press |
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2017-02-13 13:54 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-05-06 20:00 |
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Publish the Manuscript Online |
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2017-05-12 22:16 |
| ISSN |
2220-3249 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Allergy |
| Manuscript Type |
Observational Study |
| Article Title |
Matrix metalloproteases and their tissue inhibitors in
non-alcoholic liver fibrosis of human immunodeficiency virus-infected patients
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Julio Collazos, Eulalia Valle-Garay, Tomás Suárez-Zarracina, Angel-Hugo Montes, José A Cartón and Víctor Asensi |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Oviedo University research grants |
UNIOV-12-MA-03 |
| the Oviedo University research grants |
SV-PA-13-ECOEMP-57 |
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| Corresponding Author |
Dr. Julio Collazos, Infectious Diseases Unit, Hospital de Galdácano, Bº Labeaga s/n, 48960 Vizcaya, Spain. med003033@gmail.com |
| Key Words |
Human immunodeficiency virus; Hepatitis C virus; Liver fibrosis; Transient elastometry; Non-invasive fibrosis markers; Metalloproteases; Their tissue inhibitors; Genetic polymorphisms |
| Core Tip |
The role of matrix metalloproteases (MMPs) and their tissue inhibitors (TIMPs) in the development of liver fibrosis is uncertain. We determined some single nucleotide polymorphisms (SNPs), as well as the serum levels of diverse MMPs and TIMPs, in non-alcoholic, human immunodeficiency virus-infected patients with/out hepatitis C virus coinfection, to evaluate their possible relationship with liver fibrosis as assessed by transient elastometry. MMP-2 was independently associated with significant fibrosis. Likewise, MMP-2, TIMP-2 and MMP-9 were independent predictors of transient elastometry values and of other non-invasive tests of fibrosis. No SNP was significantly associated with liver fibrosis. Our findings support the value of these markers in the evaluation of fibrosis. |
| Publish Date |
2017-05-12 22:16 |
| Citation |
Collazos J, Valle-Garay E, Suárez-Zarracina T, Montes AH, Cartón JA, Asensi V. Matrix metalloproteases and their tissue inhibitors in non-alcoholic liver fibrosis of human immunodeficiency virus-infected patients. World J Virol 2017; 6(2): 36-45 |
| URL |
http://www.wjgnet.com/2220-3249/full/v6/i2/36.htm |
| DOI |
http://dx.doi.org/10.5501/wjv.v6.i2.36 |
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