Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	31187
Country	United States

Received	2016-11-03 10:00
Peer-Review Started	2016-11-04 17:45
First Decision by Editorial Office Director
Return for Revision	2016-12-15 11:58
Revised	2017-04-12 06:48
Publication Fee Transferred
Second Decision by Editor	2017-05-24 01:08
Second Decision by Editor-in-Chief	2017-05-25 20:31
Final Decision by Editorial Office Director	2017-05-31 02:37
Articles in Press	2017-05-31 02:37
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-07-26 07:20
Publish the Manuscript Online	2017-08-01 00:23

ISSN	2150-5349 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Phage therapy: An alternative to antibiotics in the age of multi-drug resistance
Manuscript Source	Invited Manuscript
All Author List	Derek M Lin, Britt Koskella and Henry C Lin
Funding Agency and Grant Number	Funding Agency Grant Number Winkler Bacterial Overgrowth Research Fund (in part)
Corresponding Author	Henry C Lin, MD, Section of Gastroenterology, New Mexico VA Health Care System, 1501 San Pedro SE, Albuquerque, NM 87108, United States. helin@salud.unm.edu
Key Words	Bacteriophage; Bacteriophage therapy; Phage; Phage therapy; Endolysin; Lysin; Multidrug resistance; Antibiotic resistance; Phage safety; Methicillin-resistant S. aureus
Core Tip	Phage therapy is widely being reconsidered as an alternative to antibiotics. The use of naturally-occurring phages to treat bacterial infection has a contentious history in western medicine. However, the emergent landscape of phage-based antimicrobials has advanced well beyond traditional methods. In this rapidly evolving field, novel technologies such as bioengineered chimeras of phage-derived lytic proteins show potential as a new class of antibacterial pharmaceuticals. This review aims to provide a topical perspective on the historical context of phage therapy, in order to highlight modern advances in phage research and innovations in the field.
Publish Date	2017-08-01 00:23
Citation	Lin DM, Koskella B, Lin HC. Phage therapy: An alternative to antibiotics in the age of multi-drug resistance. World J Gastrointest Pharmacol Ther 2017; 8(3): 162-173
URL	http://www.wjgnet.com/2150-5349/full/v8/i3/162.htm
DOI	http://dx.doi.org/10.4292/wjgpt.v8.i3.162

Full Article (PDF)	WJGPT-8-162.pdf
Full Article (Word)	WJGPT-8-162.doc
Manuscript File	31187-Review.rtf
Answering Reviewers	31187-Answering reviewers.pdf
Audio Core Tip	31187-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	31187-Conflict-of-interest statement.pdf
Copyright License Agreement	31187-Copyright assignment.pdf
Peer-review Report	31187-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	31187-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	31187-Scientific misconduct check.pdf
Scientific Editor Work List	31187-Scientific editor work list.pdf