Publication Name	World Journal of Nephrology
Manuscript ID	31213
Country	Taiwan

Received	2016-11-04 17:50
Peer-Review Started	2016-11-09 16:52
To Make the First Decision	2016-11-30 09:03
Return for Revision	2016-11-30 14:48
Revised	2017-01-20 23:20
Second Decision	2017-02-08 15:38
Accepted by Journal Editor-in-Chief	2017-02-08 15:54
Accepted by Executive Editor-in-Chief	2017-02-20 15:01
Articles in Press	2017-02-20 15:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-05-02 08:57
Publish the Manuscript Online	2017-05-04 18:19

ISSN	2220-6124 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Urology & Nephrology
Manuscript Type	Review
Article Title	Targeting cannabinoid signaling for peritoneal dialysis-induced oxidative stress and fibrosis
Manuscript Source	Unsolicited Manuscript
All Author List	Chih-Yu Yang, Yat-Pang Chau, Ann Chen, Oscar Kuang-Sheng Lee, Der-Cherng Tarng and An-Hang Yang
Funding Agency and Grant Number	Funding Agency Grant Number Ministry Of Science and Technology, Taiwan NSC 96-2628-B-075-003-MY3 Ministry Of Science and Technology, Taiwan MOST 104-2314-B-075-031 Ministry Of Science and Technology, Taiwan 105-2628-B-075-008-MY3 Taipei Veterans General Hospital, National Yang-Ming University Excellent Physician Scientists Cultivation Program 103-V-B-024 Taipei Veterans General Hospital V106D25-003-MY3-1
Corresponding Author	Dr. An-Hang Yang, Institute of Clinical Medicine, National Yang-Ming University, No. 201, Section 2, Shih-Pai Road, Taipei 11221, Taiwan. ahyang@vghtpe.gov.tw
Key Words	Reactive oxygen species; Peritoneal fibrosis; Peritoneal dialysis; Cannabinoid signaling; Oxidative stress
Core Tip	Long-term exposure to bioincompatible peri­toneal dialysis (PD) solutions frequently results in peritoneal fibrosis and ultrafiltration failure, which limits the life-long use of PD therapy. Beyond uremia per se, oxidative stress (OS) also results from chronic exposure to high glucose load, glucose degradation products, advanced glycation end products, and hypertonic stress in PD patients. Therapy targeting the cannabinoid signaling pathway has been reported in several chronic inflammatory diseases with elevated OS. In this article, we review the interaction among the cannabinoid system, inflammation, and OS, through which the health-care professionals ultimately aim to prolong the peritoneal survival of PD patients.
Publish Date	2017-05-04 18:19
Citation	Yang CY, Chau YP, Chen A, Lee OKS, Tarng DC, Yang AH. Targeting cannabinoid signaling for peritoneal dialysis-induced oxidative stress and fibrosis. World J Nephrol 2017; 6(3): 111-118
URL	http://www.wjgnet.com/2220-6124/full/v6/i3/111.htm
DOI	http://dx.doi.org/10.5527/wjn.v6.i3.111

Full Article (PDF)	WJN-6-111.pdf
Full Article (Word)	WJN-6-111.doc
Manuscript File	31213-Review.doc
Answering Reviewers	31213-Answering reviewers.pdf
Audio Core Tip	31213-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	31213-Conflict-of-interest statement.pdf
Copyright License Agreement	31213-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	31213-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	31213-Language certificate.pdf
Peer-review Report	31213-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	31213-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	31213-Scientific misconduct check.pdf
Scientific Editor Work List	31213-Scientific editor work list.pdf