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3/6/2017 1:27:00 PM | Browse: 796 | Download: 1390
Publication Name World Journal of Gastroenterology
Manuscript ID 31563
Country China
Received
2016-11-25 14:06
Peer-Review Started
2016-11-26 20:45
To Make the First Decision
2017-01-10 16:16
Return for Revision
2017-01-14 11:44
Revised
2017-01-19 17:24
Second Decision
2017-02-06 14:38
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-02-08 09:43
Articles in Press
2017-02-08 09:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-02-22 18:00
Publish the Manuscript Online
2017-03-06 13:24
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type Prospective Study
Article Title Spectral computed tomography in advanced gastric cancer: Can iodine concentration non-invasively assess angiogenesis?
Manuscript Source Unsolicited Manuscript
All Author List Xiao-Hua Chen, Ke Ren, Pan Liang, Yaru Chai, Kui-Sheng Chen and Jian-Bo Gao
Funding Agency and Grant Number
Funding Agency Grant Number
The National Natural Science Foundation of China 81271573
Corresponding Author Prof. Jian-Bo Gao, Department of Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1, East Jianshe Road, Zhengzhou 450052, Henan Province, China. jianbogaochina@163.com
Key Words Micro-vessel density; Iodine concentration; Spectral computed tomography; Vascular endothelial growth factor; Gastric cancer
Core Tip We investigated the correlation between iodine concentration (IC) value generated from spectral computed tomography (CT) and angiogenesis in gastric cancer (GC) with clinical-pathological data. Our results showed that normalized IC (nIC) in both the arterial (AP) and venous phases (VP) had a positive linear correlation with micro-vessel density. nIC-AP reflected the angiogenesis in relatively earlier and well-differentiated GC, while nIC-VP reflected this in further advanced and poorly differentiated GC. Spectral CT with quantitative IC value offers a new choice for evaluating the angiogenesis of gastric cancer noninvasively.
Publish Date 2017-03-06 13:24
Citation Chen XH, Ren K, Liang P, Chai Y, Chen KS, Gao JB. Spectral computed tomography in advanced gastric cancer: Can iodine concentration non-invasively assess angiogenesis? World J Gastroenterol 2017; 23(9): 1666-1675
URL http://www.wjgnet.com/1007-9327/full/v23/i9/1666.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i9.1666
Full Article (PDF) WJG-23-1666.pdf
Full Article (Word) WJG-23-1666.doc
Manuscript File 31563-Review.docx
Answering Reviewers 31563-Answering reviewers.pdf
Audio Core Tip 31563-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 31563-Conflict-of-interest statement.pdf
Copyright License Agreement 31563-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 31563-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20161124162737.doc
Institutional Review Board Approval Form or Document 31563-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 31563-Language certificate.pdf
Peer-review Report 31563-Peer-review(s).pdf
Scientific Misconduct Check 31563-Scientific misconduct check.pdf
Scientific Editor Work List 31563-Scientific editor work list.pdf