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2/21/2017 5:21:00 PM | Browse: 873 | Download: 1096
Publication Name World Journal of Transplantation
Manuscript ID 31588
Country Australia
Received
2016-11-26 22:13
Peer-Review Started
2016-11-29 09:07
To Make the First Decision
2016-12-14 08:49
Return for Revision
2016-12-15 14:10
Revised
2016-12-21 09:04
Second Decision
2017-01-04 16:10
Accepted by Journal Editor-in-Chief
2017-01-06 23:26
Accepted by Company Editor-in-Chief
2017-01-14 14:21
Articles in Press
2017-01-14 14:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-02-20 13:32
Publish the Manuscript Online
2017-02-21 17:21
ISSN 2220-3230 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Case Report
Article Title Mycophenolate mofetil toxicity mimicking acute cellular rejection in a small intestinal transplant
Manuscript Source Invited Manuscript
All Author List Ross Apostolov, Khashayar Asadi, Julie Lokan, Ning Kam and Adam Testro
Funding Agency and Grant Number
Corresponding Author Adam Testro, MBBS, FRACP, PhD, Head of Intestinal Rehabilitation and Transplantation, Australian Intestinal Transplant Service, Austin Health, 145 Studley Road, Heidelberg, VIC 3084, Australia. adam.testro@austin.org.au
Key Words Small intestinal transplantation; Drug toxicity; Mycophenolate mofetil; Acute cellular rejection; Immunosuppression
Core Tip Mycophenolate mofetil (MMF) is a commonly used medication for maintenance immunosuppression in small intestine transplant (SIT) recipients. Enterocolitis is a known side effect of MMF therapy, but there is little literature describing its histological manifestations in SIT recipients. Our case shows that MMF enterocolitis can mimic acute cellular rejection (ACR) and highlights the importance of attempting to biopsy the native gastrointestinal tract in SIT recipients if possible. If the native biopsy is abnormal, drug toxicity should be considered as a differential diagnosis as it may show overlapping features with ACR.
Publish Date 2017-02-21 17:21
Citation Apostolov R, Asadi K, Lokan J, Kam N, Testro A. Mycophenolate mofetil toxicity mimicking acute cellular rejection in a small intestinal transplant. World J Transplant 2017; 7(1): 98-102
URL http://www.wjgnet.com/2220-3230/full/v7/i1/98.htm
DOI http://dx.doi.org/10.5500/wjt.v7.i1.98
Full Article (PDF) WJT-7-98.pdf
Full Article (Word) WJT-7-98.doc
Manuscript File 31588-Review.docx
Answering Reviewers 31588-Answering reviewers.pdf
Audio Core Tip 31588-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 31588-Conflict-of-interest statement.pdf
Copyright License Agreement 31588-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20161126110700.pdf
Institutional Review Board Approval Form or Document 31588-Institutional review board statement.pdf
Supplementary Material Supplementary_Material_20161126111312.jpg
Peer-review Report 31588-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 31588-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 31588-Scientific misconduct check.pdf
Scientific Editor Work List 31588-Scientific editor work list.pdf