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Articles Published Processes
6/23/2017 3:40:51 AM | Browse: 843 | Download: 1655
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Received |
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2016-11-29 10:54 |
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Peer-Review Started |
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2016-12-03 22:09 |
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To Make the First Decision |
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2017-03-27 11:16 |
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Return for Revision |
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2017-03-28 13:54 |
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Revised |
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2017-04-10 21:09 |
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Second Decision |
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2017-05-02 11:07 |
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Accepted by Journal Editor-in-Chief |
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2017-05-02 17:31 |
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Accepted by Executive Editor-in-Chief |
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2017-05-15 04:01 |
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Articles in Press |
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2017-05-15 04:01 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-06-06 02:22 |
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Publish the Manuscript Online |
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2017-06-23 03:40 |
| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Basic Study |
| Article Title |
Copper as an alternative antimicrobial coating for implants - An in vitro study
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Claudia Bergemann, Sarah Zaatreh, Katharina Wegner, Kathleen Arndt, Andreas Podbielski, Rainer Bader, Cornelia Prinz, Ulrich Lembke and J Barbara Nebe |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Federal Ministry of Education and Research of Germany (BMBF) |
13N12105, project CEMOSTOBAS |
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| Corresponding Author |
Dr. J Barbara Nebe, Professor, Department of Cell Biology, University Medical Center Rostock, Schillingallee 69, 18057 Rostock, Germany. barbara.nebe@med.uni-rostock.de |
| Key Words |
Implant-coating; Antimicrobial effect; Titanium plasma spray; Titanium-copper-nitride; BONIT®; Osteoconductivity |
| Core Tip |
Implant-associated infection is the most feared complication after joint replacement. We investigated the osteoconductive and antimicrobial properties of a titanium-copper-nitride (TiCuN) film and an additional BONIT® coating on titanium. TiCuN released high amounts of copper quickly within 24 h and after 2 d, no planktonic or adherent Staphylococcus epidermidis were found on these samples. A high colonization by osteoblast-like MG 63 cells was found after pre-incubation in medium for 24 h. TiCuN inhibits the formation of bacterial bio-films on orthopedic implants by influencing the “race for the surface” to the advantage of osteoblasts. |
| Publish Date |
2017-06-23 03:40 |
| Citation |
Bergemann C, Zaatreh S, Wegner K, Arndt K, Podbielski A, Bader R, Prinz C, Lembke U, Nebe JB. Copper as an alternative antimicrobial coating for implants - An in vitro study. World J Transplant 2017; 7(3): 193-202 |
| URL |
http://www.wjgnet.com/2220-3230/full/v7/i3/193.htm |
| DOI |
http://dx.doi.org/10.5500/wjt.v7.i3.193 |
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