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Articles Published Processes
4/14/2017 6:51:01 PM | Browse: 1268 | Download: 1658
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Received |
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2016-11-30 09:28 |
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Peer-Review Started |
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2016-11-30 16:40 |
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To Make the First Decision |
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2016-12-28 16:51 |
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Return for Revision |
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2017-01-03 08:31 |
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Revised |
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2017-02-01 00:03 |
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Second Decision |
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2017-03-01 11:13 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2017-03-02 16:59 |
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Articles in Press |
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2017-03-02 16:59 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2017-03-24 05:10 |
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Typeset the Manuscript |
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2017-04-01 11:51 |
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Publish the Manuscript Online |
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2017-04-14 18:51 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is open-access and was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Comparative study of ROR2 and WNT5a expression in squamous/adenosquamous carcinoma and adenocarcinoma of the gallbladder
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Zheng-Chun Wu, Li Xiong, Ling-Xiang Wang, Xiong-Ying Miao, Zi-Ru Liu, Dai-Qiang Li, Qiong Zou, Kui-Jie Liu, Hua Zhao and Zhu-Lin Yang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the National Natural Science Foundation of China |
81372628 |
| the National Natural Science Foundation of China |
81402536 |
| Changsha Science and Technology Plan |
K1205018-31 |
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| Corresponding Author |
Dr. Zhu-Lin Yang, Research Laboratory of Hepatobiliary Diseases, Second Xiangya Hospital, Central South University, 139 Middle Renmin Rd., Changsha 410011, Hunan Province, China. 4896142@qq.com |
| Key Words |
Gallbladder adenosquamous carcinoma; Gallbladder squamous carcinoma; ROR2; Gallbladder adenocarcinoma; WNT5a; Immunohistochemistry |
| Core Tip |
Gallbladder carcinoma (GBC) is a highly aggressive malignancy of the biliary tract. However, biological markers for the diagnosis, prognosis, and targeted therapy of GBCs are still not clear. In this study, we investigated the clinicopathological significance of ROR2 and WNT5a in squamous/adenosquamous carcinoma (SC/ASC) and adenocarcinoma (AC) of the gallbladder. We found that positive ROR2 or WNT5a expression in both SC/ASC or AC patients were negatively correlated with postoperative survival rate and positively correlated with mortality. Elevated expression levels of ROR2 or WNT5a are associated with a higher risk of GBC and are independent prognostic predictors. |
| Publish Date |
2017-04-14 18:51 |
| Citation |
Wu ZC, Xiong L, Wang LX, Miao XY, Liu ZR, Li DQ, Zou Q, Liu KJ, Zhao H, Yang ZL. Comparative study of ROR2 and WNT5a expression in squamous/adenosquamous carcinoma and adenocarcinoma of the gallbladder. World J Gastroenterol 2017; 23(14): 2601-2612 |
| URL |
http://www.wjgnet. com/1007-9327/full/v23/i14/2601.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i14.2601 |
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