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4/14/2017 6:51:01 PM | Browse: 746 | Download: 383
Publication Name World Journal of Gastroenterology
Manuscript ID 31647
Country of Manuscript Source China
Received
2016-11-30 09:28
Peer-Review Started
2016-11-30 16:40
To Make the First Decision
2016-12-28 16:51
Return for Revision
2017-01-03 08:31
Revised
2017-02-01 00:03
Second Decision
2017-03-01 11:13
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-03-02 16:59
Articles in Press
2017-03-02 16:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
2017-03-24 05:10
Typeset the Manuscript
2017-04-01 11:51
Publish the Manuscript Online
2017-04-14 18:51
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is open-access and was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Oncology
Manuscript Type Clinical Trials Study
Article Title Comparative study of ROR2 and WNT5a expression in squamous/adenosquamous carcinoma and adenocarcinoma of the gallbladder
Manuscript Source Invited Manuscript
All Author List Zheng-Chun Wu, Li Xiong, Ling-Xiang Wang, Xiong-Ying Miao, Zi-Ru Liu, Dai-Qiang Li, Qiong Zou, Kui-Jie Liu, Hua Zhao and Zhu-Lin Yang
Funding Agency and Grant Number
Funding Agency Grant Number
the National Natural Science Foundation of China 81372628
the National Natural Science Foundation of China 81402536
Changsha Science and Technology Plan K1205018-31
Corresponding author Dr. Zhu-Lin Yang, Research Laboratory of Hepatobiliary Diseases, Second Xiangya Hospital, Central South University, 139 Middle Renmin Rd., Changsha 410011, Hunan Province, China. 4896142@qq.com
Keywords Gallbladder adenosquamous carcinoma; Gallbladder squamous carcinoma; ROR2; Gallbladder adenocarcinoma; WNT5a; Immunohistochemistry
Core Tip Gallbladder carcinoma (GBC) is a highly aggressive malignancy of the biliary tract. However, biological markers for the diagnosis, prognosis, and targeted therapy of GBCs are still not clear. In this study, we investigated the clinicopathological significance of ROR2 and WNT5a in squamous/adenosquamous carcinoma (SC/ASC) and adenocarcinoma (AC) of the gallbladder. We found that positive ROR2 or WNT5a expression in both SC/ASC or AC patients were nega­tively correlated with postoperative survival rate and positively correlated with mortality. Elevated expression levels of ROR2 or WNT5a are associated with a higher risk of GBC and are independent prognostic predictors.
Publish Date 2017-04-14 18:51
Citation Wu ZC, Xiong L, Wang LX, Miao XY, Liu ZR, Li DQ, Zou Q, Liu KJ, Zhao H, Yang ZL. Comparative study of ROR2 and WNT5a expression in squamous/adenosquamous carcinoma and adenocarcinoma of the gallbladder. World J Gastroenterol 2017; 23(14): 2601-2612
Url http://www.wjgnet. com/1007-9327/full/v23/i14/2601.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i14.2601
Full Article (PDF) WJG-23-2601.pdf
Full Article (Word) WJG-23-2601.doc
Manuscript File 31647-Review.docx
Answering Reviewers 31647-Answering reviewers.docx
Audio Core Tip 31647-Audio core tip.mp3
Biostatistics Review Certificate 31647-Biostatistics statement.pdf
Clinical Trial Registration Statement 31647-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form 31647-Conflict-of-interest statement.pdf
Copyright License Agreement 31647-Copyright assignment.pdf
Data Sharing Statement 31647-Data sharing statement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 31647-Grant application form(s) (3).pdf
Signed Informed Consent Form(s) or Document(s) 31647-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 31647-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 31647-Language certificate.pdf
Scientific Research Process 31647-Scientific research process.pdf
Peer-review Report 31647-Peer-review(s).pdf
Scientific Misconduct Check 31647-Scientific misconduct check.pdf
Scientific Editor Work List 31647-Scientific editor work list.pdf