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6/2/2017 5:29:41 AM | Browse: 468 | Download: 566
Publication Name World Journal of Clinical Oncology
Manuscript ID 31675
Country/Territory Brazil
2016-12-02 09:56
Peer-Review Started
2016-12-05 08:53
To Make the First Decision
2017-03-27 11:16
Return for Revision
2017-03-28 13:59
2017-04-05 10:03
Second Decision
2017-04-24 17:46
Accepted by Journal Editor-in-Chief
2017-04-26 17:02
Accepted by Company Editor-in-Chief
2017-05-05 16:04
Articles in Press
2017-05-05 16:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-05-26 04:59
Publish the Manuscript Online
2017-06-02 05:29
ISSN 2218-4333 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Systematic Review
Article Title Recurrence-free survival as a putative surrogate for overall survival in phase III trials of curative-intent treatment of colorectal liver metastases: Systematic review
Manuscript Source Invited Manuscript
All Author List Raphael LC Araujo, Paulo Herman and Rachel P Riechelmann
Funding Agency and Grant Number
Corresponding author Raphael LC Araujo, MD, PhD, Department of Upper Gastrointestinal and Hepato-Pancreato-Bliliary Sugery, Barretos Cancer Hospital, Rua Antenor Duarte Villela, 1331, Barretos, SP 14784-400, Brazil. raphael.araujo@hcancerbarretos.com.br
Keywords Colorectal liver metastases; Surgery; Chemotherapy; Clinical trial; Long-term outcomes; Surrogate endpoints
Core Tip This study addresses a systematic review of curative-intent treatment of colorectal liver metastasis looking for oncologic outcomes. We describe the association between overall survival (OS) and recurrence free survival in the setting of resectable colorectal liver metastases (CRLM). It suggests that recurrence free survival could work as a putative surrogate of OS in this population, avoiding bigger, longer and more resource-consuming trials. We do believe that our model can be useful to better estimate sample size calculations of superiority phase Ⅲ trials of CRLM aiming for OS.
Publish Date 2017-06-02 05:29
Citation Araujo RLC, Herman P, Riechelmann RP. Recurrence-free survival as a putative surrogate for overall survival in phase III trials of curative-intent treatment of colorectal liver metastases: Systematic review. World J Clin Oncol 2017; 8(3): 266-272
Url http://www.wjgnet.com/2218-4333/full/v8/i3/266.htm
DOI http://dx.doi.org/10.5306/wjco.v8.i3.266
Full Article (PDF) WJCO-8-266.pdf
Full Article (Word) WJCO-8-266.doc
Manuscript File 31675-Review.docx
Answering Reviewers 31675-Answering reviewers.pdf
Audio Core Tip 31675-Audio core tip.mp3
Biostatistics Review Certificate 31675-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 31675-Conflict-of-interest statement.pdf
Copyright License Agreement 31675-Copyright assignment.pdf
Data Sharing Statement 31675-Data sharing statement.pdf
Peer-review Report 31675-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 31675-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 31675-Scientific misconduct check.pdf
Scientific Editor Work List 31675-Scientific editor work list.pdf