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4/20/2017 3:58:56 PM | Browse: 614 | Download: 1091
Publication Name World Journal of Gastroenterology
Manuscript ID 31706
Country China
Received
2016-12-04 16:05
Peer-Review Started
2016-12-06 13:10
To Make the First Decision
2017-01-19 13:31
Return for Revision
2017-01-19 22:30
Revised
2017-02-14 00:00
Second Decision
2017-03-09 17:54
Accepted by Journal Editor-in-Chief
2017-03-09 21:18
Accepted by Company Editor-in-Chief
2017-03-15 13:35
Articles in Press
2017-03-15 13:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-04-10 19:39
Publish the Manuscript Online
2017-04-20 15:58
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Role of Δ133p53 isoform in NF-κB inhibitor PDTC-mediated growth inhibition of MKN45 gastric cancer cells
Manuscript Source Unsolicited Manuscript
All Author List Hong-Mei Zhang, Xiao-Guang Sang, Yan-Ze Wang, Can Cui, Li Zhang and Wan-Sheng Ji
Funding Agency and Grant Number
Funding Agency Grant Number
Shandong Provincial Award Foundation for Youth and Middle-aged Scientist BS2010SW034
Corresponding Author Dr. Wan-Sheng Ji, Department of Gastroenterology, Affiliated Hospital of Weifang Medical University, Weifang 261031, Shandong Province, China. wanshengji68@126.com
Key Words Gastric cancer; p53 isoforms; Nuclear factor-κB
Core Tip Intestinal-type of gastric cancer develops from chronic gastritis. Δ133p53 isoform has been recently identified as an oncogenic actor that is pivotal in Helicobacter pylori-driven progression of chronic gastritis to gastric cancerogenesis. These results suggest that Δ133p53 isoform is required in pyrrolidine dithiocarbamate-induced inhibition of MKN45 gastric cancer cells, and disturbance in the cross-talk between p53 and nuclear factor-κB pathways is a promising target in pharmaceutical research for the development of treatment strategies against intestinal-type gastric cancer.
Publish Date 2017-04-20 15:58
Citation Zhang HM, Sang XG, Wang YZ, Cui C, Zhang L, Ji WS. Role of Δ133p53 isoform in NF-κB inhibitor PDTC-mediated growth inhibition of MKN45 gastric cancer cells. World J Gastroenterol 2017; 23(15): 2716-2722
URL http://www.wjgnet.com/1007-9327/full/v23/i15/2716.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i15.2716
Full Article (PDF) WJG-23-2716.pdf
Full Article (Word) WJG-23-2716.doc
Manuscript File 31706-Review.doc
Answering Reviewers 31706-Answering reviewers.pdf
Audio Core Tip 31706-Audio core tip.mp3
Biostatistics Review Certificate 31706-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 31706-Conflict-of-intereststatement.pdf
Institutional Animal Care and Use Committee Approval Form or Document 31706-Institutional animal careand use committee statement.pdf
Institutional Review Board Approval Form or Document 31706-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 31706-Language certificate.pdf
Peer-review Report 31706-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 31706-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 31706-Scientific misconduct check.pdf
Scientific Editor Work List 31706-Scientific editor work list.pdf