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Articles Published Processes
4/20/2017 3:58:56 PM | Browse: 894 | Download: 2124
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Received |
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2016-12-04 16:05 |
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Peer-Review Started |
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2016-12-06 13:10 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2017-01-19 22:30 |
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Revised |
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2017-02-14 00:00 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2017-03-09 17:54 |
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Second Decision by Editor-in-Chief |
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2017-03-09 21:18 |
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Final Decision by Editorial Office Director |
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2017-03-15 13:35 |
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Articles in Press |
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2017-03-15 13:35 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-04-10 19:39 |
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Publish the Manuscript Online |
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2017-04-20 15:58 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Role of Δ133p53 isoform in NF-κB inhibitor PDTC-mediated growth inhibition of MKN45 gastric cancer cells
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hong-Mei Zhang, Xiao-Guang Sang, Yan-Ze Wang, Can Cui, Li Zhang and Wan-Sheng Ji |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Shandong Provincial Award Foundation for Youth and Middle-aged Scientist |
BS2010SW034 |
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| Corresponding Author |
Dr. Wan-Sheng Ji, Department of Gastroenterology, Affiliated Hospital of Weifang Medical University, Weifang 261031, Shandong Province, China. wanshengji68@126.com |
| Key Words |
Gastric cancer; p53 isoforms; Nuclear factor-κB |
| Core Tip |
Intestinal-type of gastric cancer develops from chronic gastritis. Δ133p53 isoform has been recently identified as an oncogenic actor that is pivotal in Helicobacter pylori-driven progression of chronic gastritis to gastric cancerogenesis. These results suggest that Δ133p53 isoform is required in pyrrolidine dithiocarbamate-induced inhibition of MKN45 gastric cancer cells, and disturbance in the cross-talk between p53 and nuclear factor-κB pathways is a promising target in pharmaceutical research for the development of treatment strategies against intestinal-type gastric cancer. |
| Publish Date |
2017-04-20 15:58 |
| Citation |
Zhang HM, Sang XG, Wang YZ, Cui C, Zhang L, Ji WS. Role of Δ133p53 isoform in NF-κB inhibitor PDTC-mediated growth inhibition of MKN45 gastric cancer cells. World J Gastroenterol 2017; 23(15): 2716-2722
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| URL |
http://www.wjgnet.com/1007-9327/full/v23/i15/2716.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i15.2716 |
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