Publication Name	World Journal of Cardiology
Manuscript ID	31719
Country	United States

Received	2016-12-05 11:20
Peer-Review Started	2016-12-05 14:40
To Make the First Decision	2016-12-19 08:55
Return for Revision	2016-12-20 18:07
Revised	2017-05-27 20:50
Second Decision	2017-07-06 09:05
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-07-17 08:13
Articles in Press	2017-07-17 08:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-08-18 07:58
Publish the Manuscript Online	2017-08-24 04:57

ISSN	1949-8462 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Review
Article Title	Diagnosis and management challenges of in-stent restenosis in coronary arteries
Manuscript Source	Invited Manuscript
All Author List	M Chadi Alraies, Fahed Darmoch, Ramyashree Tummala and Ron Waksman
Funding Agency and Grant Number
Corresponding Author	M Chadi Alraies, MD, Heart and Vascular Institute, Department of Interventional Cardiology, Georgetown University/MedStar Washington Hospital Center, 110 Irving Street, NW, Suite 4B-1, Washington, DC 20010, United States. mchadi.alraies@medstar.net
Key Words	Stent; In-stent; Restenosis; Percutaneous coronary intervention
Core Tip	Percutaneous coronary intervention with stenting is currently the most widely performed procedure for the treatment of symptomatic coronary disease. In large trials, drug-eluting stents (DES) have led to a significant reduction in in-stent restenosis (ISR) rates, one of the major limitations of bare-metal stents. However, ISR remains a serious concern as late stent complications. ISR mainly results from aggressive neointimal proliferation and neoatherosclerosis. DES-ISR treatment continues to be challenging complications for interventional cardiologists. This review focuses on pathogenesis, diagnosis and treatment options for ISR in the current era of advanced intravascular imaging and intervention.
Publish Date	2017-08-24 04:57
Citation	Alraies MC, Darmoch F, Tummala R, Waksman R. Diagnosis and management challenges of in-stent restenosis in coronary arteries. World J Cardiol 2017; 9(8): 640-651
URL	http://www.wjgnet.com/1949-8462/full/v9/i8/640.htm
DOI	http://dx.doi.org/10.4330/wjc.v9.i8.640

Full Article (PDF)	WJC-9-640.pdf
Full Article (Word)	WJC-9-640.doc
Manuscript File	31719-Review.docx
Answering Reviewers	31719-Answering reviewers.pdf
Audio Core Tip	31719-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	31719-Conflict-of-interest statement.pdf
Copyright License Agreement	31719-Copyright assignment.pdf
Peer-review Report	31719-Peer-review(s).pdf
Scientific Misconduct Check	31719-Scientific misconduct check.pdf
Scientific Editor Work List	31719-Scientific editor work list.pdf