Publication Name	World Journal of Gastroenterology
Manuscript ID	3173
Country	China

Received	2013-04-12 07:48
Peer-Review Started	2013-04-12 11:38
To Make the First Decision	2013-05-14 18:48
Return for Revision	2013-05-20 10:00
Revised	2013-06-18 19:49
Second Decision	2013-08-16 19:47
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-08-17 00:17
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-09-09 15:35
Publish the Manuscript Online	2013-09-21 09:08

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Website	http://www.wjgnet.com

Category	Pediatrics
Manuscript Type	Autobiography
Article Title	Association between UCP3 gene polymorphisms and nonalcoholic fatty liver disease in Chinese children
Manuscript Source	Invited Manuscript
All Author List	Yan-Ping Xu, Li Liang, Chun-Lin Wang, Jun-Fen Fu, Pei-Ning Liu, Lan-Qiu Lv and Yi-Min Zhu
Funding Agency and Grant Number	Funding Agency Grant Number Zhejiang Provincial Natural Science Foundation of China Y2090137 National Key Technology R and D Program of China 2012BAI02B03 Fundamental Research Funds for the Central Universities, Ministry of Education, China 2011KYJD008 National Natural Science Foundation of China J20121252 National Natural Science Foundation of China 81200460
Corresponding Author	Li Liang, Professor, Department of Pediatrics, the First Affiliated Hospital, College of Medicine, Zhejiang University; 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. zdliangli@163.com
Key Words	Nonalcoholic fatty liver disease; Uncoupling protein 3; Single nucleotide polymorphisms
Core Tip	There are few population-based prevalence studies of pediatric nonalcoholic fatty liver disease (NAFLD). Uncoupling protein 3 (UCP3) is considered to be associated with obesity, given the role for UCP3 in the regulation of energy and lipid metabolism. This is the first study to report that there significant difference of body height, waist and hip circumference between CC (mutant type group) and CT+TT group with and without rs1800849 variation were found. This study confirmed the hypothesis that polymorphisms of the UCP3 are associated with the occurrence of NAFLD. These variations could be useful for the diagnosis and/or prognosis of NAFLD.
Publish Date	2013-09-21 09:08
Citation	Xu YP, Liang L, Wang CL, Fu JF, Liu PN, Lv LQ, Zhu YM. Association between UCP3 gene polymorphisms and nonalcoholic fatty liver disease in Chinese children. World J Gastroenterol 2013; 19(35): 5897-5903
URL	http://www.wjgnet.com/1007-9327/full/v19/i35/5897.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i35.5897

Full Article (PDF)	WJG-19-5897.pdf
Manuscript File	3173-Review.doc
Answering Reviewers	3173-Answering Reviewers.pdf
Copyright License Agreement	3173-Copyright Assignment.pdf
Non-Native Speakers of English Editing Certificate	3173-Language certificate.pdf
Peer-review Report	3173-Peer review(s).pdf
Scientific Editor Work List	3173-Scientific editor work list.doc