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Articles Published Processes
9/1/2014 3:13:00 PM | Browse: 1353 | Download: 1206
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Received |
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2013-04-12 07:58 |
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Peer-Review Started |
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2013-04-12 11:36 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2013-05-20 09:51 |
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Revised |
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2013-06-03 22:36 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2013-06-19 12:58 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2013-06-20 01:06 |
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Articles in Press |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-07-31 15:25 |
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Publish the Manuscript Online |
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2013-08-15 11:51 |
| Category |
Urology & Nephrology |
| Manuscript Type |
Minireviews |
| Article Title |
Diabetic nephropathy: Treatment with phosphodiesterase type 5 inhibitors
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Cecil Stanley Thompson |
| Funding Agency and Grant Number |
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| Corresponding Author |
Cecil Stanley Thompson, PhD, Department of Surgery, Division of Surgery and Interventional Science, University College London Medical School, Royal Free Campus, Pond Street, London NW3 2QG, United Kingdom. cecil.thompson@nhs.net |
| Key Words |
Diabetic nephropathy; Phosphodiesterase type 5; Glomerular filtration rate; Inflammation; Angiotensin Ⅱ |
| Core Tip |
Diabetic nephropathy a leading cause of end-stage renal disease, is characterized by dysfunctional metabolic, haemodynamic and inflammatory pathways leading to glomerular hypertension. These pathways were normalized following treatment with phosphodiesterase type 5 inhibitors, which initiated renal vascular smooth muscle relaxation. This therapeutic option for treating diabetic nephropathy may negate the need for costly renal dialysis or transplantation. |
| Publish Date |
2013-08-15 11:51 |
| Citation |
Thompson CS. Diabetic nephropathy: Treatment with phosphodiesterase type 5 inhibitors. World J Diabetes 2013; 4(4): 124-129 |
| URL |
http://www.wjgnet.com/1948-9358/full/v4/i4/124.htm |
| DOI |
http://dx.doi.org/10.4239/wjd.v4.i4.124 |
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