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5/15/2017 6:16:31 AM | Browse: 987 | Download: 1369
Publication Name World Journal of Gastroenterology
Manuscript ID 31762
Country China
Received
2016-12-06 10:40
Peer-Review Started
2016-12-06 21:50
To Make the First Decision
2016-12-29 09:10
Return for Revision
2016-12-30 10:34
Revised
2017-01-24 23:45
Second Decision
2017-03-17 17:24
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-03-20 16:39
Articles in Press
2017-03-20 16:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
2017-04-06 12:14
Typeset the Manuscript
2017-04-21 16:44
Publish the Manuscript Online
2017-05-15 06:16
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Basic Study
Article Title Artificial liver support in pigs with acetaminophen-induced acute liver failure
Manuscript Source Unsolicited Manuscript
All Author List Guo-Lin He, Lei Feng, Lei Cai, Chen-Jie Zhou, Yuan Cheng, Ze-Sheng Jiang, Ming-Xin Pan and Yi Gao
Funding Agency and Grant Number
Corresponding Author Dr. Yi Gao, Department of Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University, Number 253 Industry Road, Hai Zhu District, Guangdong Province, Guangzhou 510280, Guangdong Province, China. gaoyizjyy@126.com
Key Words Hepatic failure; Acetaminophen; Artificial liver; Acute liver failure; Liver-assisted device
Core Tip This is an article about an artificial liver system that was used to treat an acetaminophen (APAP)-induced porcine acute liver failure (ALF) model. An APAP porcine ALF model was set up and treated by an artificial liver system. The artificial liver system(ZHJ-3) improved serum biochemistry levels and extended porcine survival times significantly. This study concluded that the APAP-induced model is reproducible and and allow for the mensurable evaluation of new liver systems, such as a bioartificial liver, for the support of hepatic failure in humans. The artificial liver system(ZHJ-3) is safe and effective for APAP-induced porcine ALF model.
Publish Date 2017-05-15 06:16
Citation He GL, Feng L, Cai L, Zhou CJ, Cheng Y, Jiang ZS, Pan MX, Gao Y. Artificial liver support in pigs with acetaminophen-induced acute liver failure. World J Gastroenterol 2017; In press
URL http://www.wjgnet.com/1007-9327/full/v23/i18/3262.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i18.3262
Full Article (PDF) WJG-23-3262.pdf
Full Article (Word) WJG-23-3262.doc
Manuscript File 31762-Review.docx
Answering Reviewers 31762-Answering reviewers.pdf
Audio Core Tip 31762-Audio core tip.mp3
Biostatistics Review Certificate 31762-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 31762-Conflict-of-interest statement.pdf
Copyright License Agreement 31762-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 31762-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 31762-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 31762-Language certificate.pdf
Peer-review Report 31762-Peer-review(s).pdf
Scientific Misconduct Check 31762-Scientific misconduct check.pdf
Scientific Editor Work List 31762-Scientific editor work list.pdf