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4/14/2017 6:51:01 PM | Browse: 962 | Download: 1142
Publication Name World Journal of Gastroenterology
Manuscript ID 31774
Country China
Received
2016-12-07 10:31
Peer-Review Started
2016-12-08 08:21
To Make the First Decision
2016-12-29 09:10
Return for Revision
2016-12-30 10:35
Revised
2017-01-11 22:06
Second Decision
2017-02-15 21:10
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2017-02-17 13:12
Articles in Press
2017-02-17 13:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
2017-03-22 20:48
Typeset the Manuscript
2017-04-01 14:24
Publish the Manuscript Online
2017-04-14 18:51
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Physiology
Manuscript Type Minireviews
Article Title New progress in roles of nitric oxide during hepatic ischemia reperfusion injury
Manuscript Source Unsolicited Manuscript
All Author List Ya-Qi Zhang, Ning Ding, Yong-Fen Zeng, Yuan-Yuan Xiang, Mei-Wen Yang, Fen-Fang Hong and Shu-Long Yang
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81260504
National Natural Science Foundation of China 81660151
National Natural Science Foundation of China 81660751
Science Foundation of Science Commission of Jiang Xi Province in China 20161BBG70067
School Teaching Reform foundation of Nanchang University NCUJGLX - 14-1-111
Corresponding Author Shu-long Yang, PhD, Professor, Department of Physiology, Basic Medical College, Nanchang University, 461 Bayi Road, Nanchang 330006, Jiangxi Province, China. slyang@ncu.edu.cn
Key Words Liver; Hepatic ischemia reperfusion injury; Nitric oxide; Nitric oxide synthase
Core Tip The latest findings on the role of nitric oxide (NO) during hepatic ischemia reperfusion injury (HIRI) include: NO exerts a protective effect against HIRI by increasing NO bioavailability, downregulating p53 gene expression, decreasing inflammatory chemokines, reducing ROS by inhibiting the mitochondrial respiratory chain, activating sGC-GTP-cGMP signal pathway to reduce liver cell apoptosis, and regulating hepatic immune functions; eNOS protects against HIRI by increasing NO levels, several eNOS/NO signal pathways (such as Akt-eNOS/NO, AMPK-eNOS/NO and HIF-1α-eNOS/NO) participating in the anti-HIRI process; inhibiting over-expression of eNOS also protects against HIRI; and finally, the inhibition of iNOS prevented HIRI.
Publish Date 2017-04-14 18:51
Citation Zhang YQ, Ding N, Zeng YF, Xiang YY, Yang MW, Hong FF, Yang SL. New progress in roles of nitric oxide during hepatic ischemia reperfusion injury. World J Gastroenterol 2017; 23(14): 2505-2510
URL http://www.wjgnet. com/1007-9327/full/v23/i14/2505.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i14.2505
Full Article (PDF) WJG-23-2505.pdf
Full Article (Word) WJG-23-2505.doc
Manuscript File 31774-Review.doc
Answering Reviewers 31774-Answering reviewers.pdf
Audio Core Tip 31774-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 31774-Conflict-of-interest statement.pdf
Copyright License Agreement 31774-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 31774-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 31774-Language certificate.pdf
Peer-review Report 31774-Peer-review(s).pdf
Scientific Misconduct Check 31774-Scientific misconduct check.pdf
Scientific Editor Work List 31774-Scientific editor work list.pdf