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Articles Published Processes
3/19/2017 6:44:00 PM | Browse: 1041 | Download: 1998
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Received |
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2016-12-09 09:02 |
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Peer-Review Started |
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2016-12-09 16:25 |
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To Make the First Decision |
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2016-12-29 09:10 |
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Return for Revision |
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2016-12-30 10:36 |
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Revised |
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2017-01-06 18:28 |
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Second Decision |
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2017-02-15 21:12 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-02-17 13:14 |
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Articles in Press |
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2017-02-17 13:14 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-03-03 09:11 |
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Publish the Manuscript Online |
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2017-03-19 18:45 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Infection does not increase long-term mortality in patients with acute severe alcoholic hepatitis treated with corticosteroids
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ashwin D Dhanda, Ashish Sinha, Vicky Hunt, Sarah Saleem, Matthew E Cramp and Peter L Collins |
| Funding Agency and Grant Number |
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| Corresponding Author |
Ashwin D Dhanda, BSc (Hons), MBChB, MRCP, PhD, Institute of Translational and Stratified Medicine, Plymouth University Peninsula Schools of Medicine and Dentistry, John Bull Building, Research Way, Plymouth PL6 8BU, United Kingdom. ashwin.dhanda@plymouth.ac.uk |
| Key Words |
Alcoholic hepatitis; Escherichia; Infection; Lille score; Corticosteroids |
| Core Tip |
Corticosteroids are the only treatment shown to improve outcome in patients with acute severe alcoholic hepatitis (AAH) but may be associated with increased rates of infection and mortality. In this prospective cohort study of patients with AAH treated with corticosteroids rates of clinically relevant infections were accurately documented. Half of the study participants developed an infection during their hospitalisation with the commonest sites being ascites and bacteraemia. Infection was associated with higher creatinine, model for end-stage liver disease and lille score but not with higher 90-d or 1 year mortality. Infection is common in patients with AAH but is not associated with increased mortality. |
| Publish Date |
2017-03-19 18:45 |
| Citation |
Dhanda AD, Sinha A, Hunt V, Saleem S, Cramp ME, Collins PL. Infection does not increase long-term mortality in patients with acute severe alcoholic hepatitis treated with corticosteroids. World J Gastroenterol 2017; 23(11): 2052-2059 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i11/2052.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i11.2052 |
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