Publication Name	World Journal of Hepatology
Manuscript ID	31863
Country	United Kingdom

Received	2016-12-12 08:23
Peer-Review Started	2016-12-13 10:45
To Make the First Decision	2017-03-13 10:36
Return for Revision	2017-03-17 11:24
Revised	2017-04-14 17:07
Second Decision	2017-06-21 00:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-07-03 02:45
Articles in Press	2017-07-03 02:45
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-07-16 13:15
Publish the Manuscript Online	2017-07-25 10:25

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Outcomes of pregnancy in patients with known Budd-Chiari syndrome
Manuscript Source	Invited Manuscript
All Author List	Faisal Khan, Ian Rowe, Bill Martin, Ellen Knox, Tracey Johnston, Charlie Elliot, Will Lester, Frederick Chen, Simon Olliff, Homoyon Mehrzad, Zergham Zia and Dhiraj Tripathi
Funding Agency and Grant Number
Corresponding Author	Faisal Khan, Liver Unit, Queen Elizabeth Hospital, Mindelsohn Way, Birminghamv B15 2TH, United Kingdom. faisalkhan@doctors.org.uk
Key Words	Budd-Chiari syndrome; Pregnancy; Portal hypertension; Pulmonary hypertension; Thrombophilia
Core Tip	Pregnancy is a prothrombotic state and can cause adverse outcome in patients with Budd-Chiari syndrome (BCS). In our study, maternal outcome in patients with known and treated BCS was good. However, most deliveries were carried out by emergency caesarean section (7/10). There was high incidence of placental disease leading to caesarean section. Fetal outcome beyond 20 wk gestation was also good. With careful monitoring of anti-coagulation, there were no cases of thrombosis and only a minority of patients had noteworthy bleeding complications. Development of pulmonary hypertension in two patients several years after TIPSS is an important finding that warrants further studies.
Publish Date	2017-07-25 10:25
Citation	Khan F, Rowe I, Martin B, Knox E, Johnston T, Elliot C, Lester W, Chen F, Olliff S, Mehrzad H, Zia Z, Tripathi D. Outcomes of pregnancy in patients with known Budd-Chiari syndrome. World J Hepatol 2017; 9(21): 945-952
URL	http://www.wjgnet.com/1948-5182/full/v9/i21/945.htm
DOI	http://dx.doi.org/10.4254/wjh.v9.i21.945

Full Article (PDF)	WJH-9-945.pdf
Full Article (Word)	WJH-9-945.doc
Manuscript File	31863-Review.docx
Answering Reviewers	31863-Answering reviewers.pdf
Audio Core Tip	31863-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	31863-Conflict-of-interest statement.pdf
Copyright License Agreement	31863-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	31863-Institutional review board statement.pdf
Peer-review Report	31863-Peer-review(s).pdf
Scientific Misconduct Check	31863-Scientific misconduct check.pdf
Scientific Editor Work List	31863-Scientific editor work list.pdf