Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	31955
Country	Ireland

Received	2016-12-18 10:59
Peer-Review Started	2016-12-20 11:31
To Make the First Decision	2017-03-06 18:01
Return for Revision	2017-03-10 19:25
Revised	2017-03-31 21:07
Second Decision	2017-05-11 13:57
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-05-19 03:19
Articles in Press	2017-05-19 03:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-08-03 03:55
Publish the Manuscript Online	2017-08-14 01:56

ISSN	2150-5330 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Prospective Study
Article Title	Assessment of serum angiogenic factors as a diagnostic aid for small bowel angiodysplasia in patients with obscure gastrointestinal bleeding and anaemia
Manuscript Source	Invited Manuscript
All Author List	Grainne Holleran, Mary Hussey, Sinead Smith and Deirdre McNamara
Funding Agency and Grant Number
Corresponding Author	Grainne Holleran, MD, Department of Clinical Medicine, Trinity Centre for Health Sciences, Tallaght Hospital, 24 Dublin, Ireland. hollerag@tcd.ie
Key Words	Angiodysplasia; Small intestinal bleeding; Capsule endoscopy; Angiogenic factors; Angiopoietin-2
Core Tip	Small bowel angiodysplasia (SBA) is an important cause of obscure gastrointestinal bleeding and anaemia but can be difficult to diagnose. This paper assesses the use of novel serum angiogenic factors associated with SBA as potential diagnostic aids. The study has identified a cut-off serum level of Ang2 of 2600 pg/mL which may be useful in predicting patients with the condition. Further studies will be required to determine its use in clinical practice but it may represent a major advancement in the identification of a diagnostic and prognostic marker for angiodysplasia, and also in determining the underlying pathophysiology of the condition.
Publish Date	2017-08-14 01:56
Citation	Holleran G, Hussey M, Smith S, McNamara D. Assessment of serum angiogenic factors as a diagnostic aid for small bowel angiodysplasia in patients with obscure gastrointestinal bleeding and anaemia. World J Gastrointest Pathophysiol 2017; 8(3): 127-132
URL	http://www.wjgnet.com/2150-5330/full/v8/i3/127.htm
DOI	http://dx.doi.org/10.4291/wjgp.v8.i3.127

Full Article (PDF)	WJGP-8-127.pdf
Full Article (Word)	WJGP-8-127.doc
Manuscript File	31955-Review.docx
Answering Reviewers	31955-Answering reviewers.pdf
Audio Core Tip	31955-Audio core tip.mp3
Biostatistics Review Certificate	31955-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	31955-Conflict-of-interest statement.pdf
Copyright License Agreement	31955-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	31955-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	31955-Institutional review board statement.pdf
Peer-review Report	31955-Peer-review(s).pdf
Scientific Misconduct Check	31955-Scientific misconduct check.pdf
Scientific Editor Work List	31955-Scientific editor work list.pdf