Publication Name	World Journal of Orthopedics
Manuscript ID	31969
Country	Greece

Received	2016-12-19 09:19
Peer-Review Started	2016-12-20 08:25
To Make the First Decision	2017-01-14 10:46
Return for Revision	2017-01-28 13:39
Revised	2017-02-05 16:27
Second Decision	2017-04-10 18:01
Accepted by Journal Editor-in-Chief	2017-04-12 10:30
Accepted by Executive Editor-in-Chief	2017-04-20 08:44
Articles in Press	2017-04-20 08:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-07-04 03:37
Publish the Manuscript Online	2017-07-13 12:32

ISSN	2218-5836 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Orthopedics
Manuscript Type	Minireviews
Article Title	Use of recombinant human bone morphogenetic protein-2 in spine surgery
Manuscript Source	Invited Manuscript
All Author List	Marios Lykissas and Ioannis Gkiatas
Funding Agency and Grant Number
Corresponding Author	Marios Lykissas, MD, Department of Spine Surgery, Metropolitan Hospital, Ethnarxou Makariou 9 & El. Venizelou 1, 18547 Athens, Greece. mariolyk@yahoo.com
Key Words	Recombinant human bone morphogenetic protein-2; Spine; Fusion; Bone graft; Yale University Open Data project
Core Tip	The use of recombinant human bone morpho­genetic protein-2 is widely used in spine surgery not only in approved indications but also in off-label indi­cations. Despite its ability to promote fusion there are many reported disadvantages. That’s why the Yale University Open Data project aims to serve both the patients but also the companies which fund the vast majority of research in medical products.
Publish Date	2017-07-13 12:32
Citation	Lykissas M, Gkiatas I. Use of recombinant human bone morpho­genetic protein-2 in spine surgery. World J Orthop 2017; 8(7): 531-535
URL	http://www.wjgnet.com/2218-5836/full/v8/i7/531.htm
DOI	http://dx.doi.org/10.5312/wjo.v8.i7.531

Full Article (PDF)	WJO-8-531.pdf
Full Article (Word)	WJO-8-531.doc
Manuscript File	31969-Review.docx
Answering Reviewers	31969-Answering reviewers.pdf
Audio Core Tip	31969-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	31969-Conflict-of-interest statement.pdf
Copyright License Agreement	31969-Copyright assignment.pdf
Peer-review Report	31969-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	31969-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	31969-Scientific misconduct check.pdf
Scientific Editor Work List	31969-Scientific editor work list.pdf