Publication Name	World Journal of Hepatology
Manuscript ID	3204
Country	Türkiye

Received	2013-04-14 17:10
Peer-Review Started	2013-04-15 16:36
To Make the First Decision	2013-05-02 09:05
Return for Revision	2013-05-06 11:28
Revised	2013-05-10 20:33
Second Decision	2013-07-18 15:17
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-07-19 04:03
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-08-24 17:00
Publish the Manuscript Online	2013-09-20 12:54

ISSN	1948-5182 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Noninvasive assessment of liver damage in chronic hepatitis B
Manuscript Source	Invited Manuscript
All Author List	Mehmet Celikbilek, Serkan Dogan, Sebnem Gursoy, Gokmen Zararsız, Alper Yurci, Omer Ozbakır, Kadri Guven and Mehmet Yucesoy
Funding Agency and Grant Number
Corresponding Author	Mehmet Celikbilek, MD, Department of Gastroenterology, Medical School, Bozok University, 66200 Yozgat, Turkey. drcelikbilek@yahoo.com
Key Words	Chronic hepatitis B; Fibrosis; Liver cirrhosis; Noninvasive; Serum markers
Core Tip	Due to the limitations of liver biopsy, the use of non-invasive markers has emerged in recent years. The aspartate aminotransferase/platelet ratio index (APRI) is used to determine chronic hepatitis C patients with advanced fibrosis. Neutrophil-lymphocyte (N/L) ratio is higher in patients with advanced fibrosis and considered as a novel non-invasive marker to predict advanced disease in non-alcoholic steatohepatitis. This study showed that N/L ratio is negatively correlated with HAI in chronic hepatitis B (CHB). APRI score may be useful to exclude cirrhosis in CHB patients.
Publish Date	2013-09-20 12:54
Citation	Celikbilek M, Dogan S, Gursoy S, Zarars?z G, Yurci A, Ozbak?r O, Guven K, Yucesoy M. Noninvasive assessment of liver damage in chronic hepatitis B. World J Hepatol 2013; 5(8): 439-445
URL	http://www.wjgnet.com/1948-5182/full/v5/i8/439.htm
DOI	http://dx.doi.org/10.4254/wjh.v5.i8.439

Full Article (PDF)	WJH-5-439.pdf
Manuscript File	3210-Review.doc
Answering Reviewers	3210-Answering reviewers.pdf
Copyright License Agreement	3204-Copyright assignment.pdf
Peer-review Report	3204-Peer review(s).pdf
Scientific Editor Work List	3204-Scientific editor work list.doc