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Articles Published Processes
3/19/2017 6:44:00 PM | Browse: 1153 | Download: 2345
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Received |
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2016-12-22 10:37 |
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Peer-Review Started |
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2016-12-23 15:00 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2017-01-14 11:48 |
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Revised |
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2017-01-19 16:00 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2017-02-15 19:14 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2017-02-17 09:15 |
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Articles in Press |
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2017-02-17 09:15 |
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Edit the Manuscript by Language Editor |
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2017-02-25 11:59 |
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Typeset the Manuscript |
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2017-03-07 18:06 |
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Publish the Manuscript Online |
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2017-03-19 18:45 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Radiology, Nuclear Medicine & Medical Imaging |
| Manuscript Type |
Basic Study |
| Article Title |
Chemotherapy response evaluation in a mouse model of gastric cancer using intravoxel incoherent motion diffusion-weighted MRI and histopathology
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jin Cheng, Yi Wang, Chun-Fang Zhang, He Wang, Wei-Zhen Wu, Feng Pan, Nan Hong and Jie Deng |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Research and Development Funds of Peking University People's Hospital |
RDB2015-04 |
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| Corresponding Author |
Yi Wang, MD, Department of Radiology, Peking University People’s Hospital, 11 Xizhimen South St., Beijing 100044, China. wangyi@pkuph.edu.cn |
| Key Words |
Xenografts; Intravoxel incoherent diffusion-weighted magnetic resonance imaging; Chemotherapy; Treatment response; Gastric adenocarcinoma |
| Core Tip |
In a mouse gastric cancer model, we de-monstrated that the intravoxel incoherent motion (IVIM)-derived tissue perfusion coefficient (D*) decreased, whereas perfusion fraction (PF) increased immediately after chemotherapy and during the treatment course. No considerable overlaps were observed in D* and PF measurements between the treated and control groups. IVIM-derived perfusion measurements offer a potential accurate evaluation of chemotherapeutic efficacy. This imaging study is ready to be translated into a clinical study and may facilitate individualized treatment strategy and prompt treatment adjustment in gastric cancer patients. |
| Publish Date |
2017-03-19 18:45 |
| Citation |
Cheng J, Wang Y, Zhang CF, Wang H, Wu WZ, Pan F, Hong N, Deng J. Chemotherapy response evaluation in a mouse model of gastric cancer using intravoxel incoherent motion diffusion-weighted MRI and histopathology. World J Gastroenterol 2017; 23(11): 1990-2001
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| URL |
http://www.wjgnet.com/1007-9327/full/v23/i11/1990.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i11.1990 |
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