Publication Name	World Journal of Gastroenterology
Manuscript ID	32080
Country	Malaysia

Received	2016-12-24 16:50
Peer-Review Started	2016-12-28 16:55
To Make the First Decision	2017-04-21 10:34
Return for Revision	2017-04-26 19:48
Revised	2017-05-08 09:19
Second Decision	2017-07-21 07:56
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-07-24 07:57
Articles in Press	2017-07-24 07:57
Publication Fee Transferred
Edit the Manuscript by Language Editor	2017-08-04 20:46
Typeset the Manuscript	2017-08-17 00:09
Publish the Manuscript Online	2017-08-28 06:54

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Comparison between tocotrienol and omeprazole on gastric growth factors in stress-exposed rats
Manuscript Source	Invited Manuscript
All Author List	Mohd Fahami Nur Azlina, Hj Mohd Saad Qodriyah, Kien Hui Chua and Yusof Kamisah
Funding Agency and Grant Number	Funding Agency Grant Number Universiti Kebangsaan Malaysia FF-032-2012 Universiti Kebangsaan Malaysia UKM-DLP-066-2011
Corresponding Author	Mohd Fahami Nur Azlina, DVM, PhD, Associate Professor, Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia. nurazlinamf@ukm.edu.my
Key Words	Tocotrienol; Omeprazole; Restraint-stress; Gastric ulcers; Growth factors
Core Tip	During the process of ulcer healing, growth factors such as epidermal growth factor, transforming growth factor-alpha, basic fibroblast growth factor and vascular endothelial growth factor acts by activating the migration of cells from the edge of the ulcer and cell proliferation together with the formation of granulation tissue and angiogenesis. Rats exposed to stress develop gastric mucosal ulcers and changes in expression of these growth factors surrounding the ulcers had been reported. Tocotrienol effects on gastric mucosal growth factors were compared to those by omeprazole in this study. The findings suggest that in contrast with omeprazole, tocotrienol has a protective effect on the gastric mucosa through its effect on these growth factors.
Publish Date	2017-08-28 06:54
Citation	Nur Azlina MF, Qodriyah HMS, Chua KH, Kamisah Y. comparison between tocotrienol and omeprazole on gastric growth factors in stress-exposed rats. World J Gastroenterol 2017; 23(32): 5887-5894
URL	http://www.wjgnet.com/1007-9327/full/v23/i32/5887.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i32.5887

Full Article (PDF)	WJG-23-5887.pdf
Full Article (Word)	WJG-23-5887.doc
Manuscript File	32080-Review.docx
Answering Reviewers	32080-Answering reviewers.pdf
Audio Core Tip	32080-Audio core tip.m4a
Biostatistics Review Certificate	32080-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	32080-Conflict-of-interest statement.pdf
Copyright License Agreement	32080-Copyright assignment.PDF
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	32080-Grant application form(s).PDF
Institutional Animal Care and Use Committee Approval Form or Document	32080-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate	32080-Language certificate.pdf
Supplementary Material	32080_Revise manuscript with markup.docm
Peer-review Report	32080-Peer-review(s).pdf
Scientific Misconduct Check	32080-Scientific misconduct check.pdf
Scientific Editor Work List	32080-Scientific editor work list.pdf