Publication Name	World Journal of Gastroenterology
Manuscript ID	32174
Country	Germany

Received	2016-12-28 10:21
Peer-Review Started	2016-12-28 17:22
To Make the First Decision	2017-02-10 08:44
Return for Revision	2017-02-13 13:15
Revised	2017-02-27 02:56
Second Decision	2017-05-04 16:32
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-05-09 17:07
Articles in Press	2017-05-09 17:07
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-06-08 09:00
Publish the Manuscript Online	2017-06-20 12:12

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Induction of chronic cholestasis without liver cirrhosis - Creation of an animal model
Manuscript Source	Invited Manuscript
All Author List	Felix Dondorf, René Fahrner, Michael Ardelt, Eleonora Patsenker, Felix Stickel, Uta Dahmen, Utz Settmacher and Falk Rauchfuß
Funding Agency and Grant Number
Corresponding Author	Falk Rauchfuß, MD, MSc, Department of General, Visceral and Vascular Surgery, Jena University Hospital, Kollegiengasse 10, 07740 Jena, Germany. falk.rauchfuss@med.uni-jena.de
Key Words	Rats; Cholestasis; Chronic cholestasis; Rat liver model
Core Tip	Animal research models mostly address either acute cholestasis or secondary biliary cirrhosis, neither of which reflect the clinical reality of central liver tumors with cholestatic liver damage without secondary liver cirrhosis. In this work, we present our data from a model simulating chronic cholestatic liver damage in an otherwise healthy liver.
Publish Date	2017-06-20 12:12
Citation	Dondorf F, Fahrner R, Ardelt M, Patsenker E, Stickel F, Dahmen U, Settmacher U, Rauchfuß F. Induction of chronic cholestasis without liver cirrhosis - Creation of an animal model. World J Gastroenterol 2017; 23(23): 4191-4199
URL	http://www.wjgnet.com/1007-9327/full/v23/i23/4191.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i23.4191

Full Article (PDF)	WJG-23-4191.pdf
Full Article (Word)	WJG-23-4191.doc
Manuscript File	32174-Review.docx
Answering Reviewers	32174-Answering reviewers.pdf
Audio Core Tip	32174-Audio core tip.mp3
Biostatistics Review Certificate	Biostatistics_Statement_20161227205232.docx
Clinical Trial Registration Statement	DeclarationOf_HelsinkiConformation_Statement_20161227204805.docx
Conflict-of-Interest Disclosure Form	32174-Conflict-of-interest statement.pdf
Copyright License Agreement	32174-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20161227204637.docx
Institutional Animal Care and Use Committee Approval Form or Document	32174-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	32174-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	32174-Language certificate.pdf
Peer-review Report	32174-Peer-review(s).pdf
Scientific Misconduct Check	32174-Scientific misconduct check.pdf
Scientific Editor Work List	32174-Scientific editor work list.pdf