Publication Name	World Journal of Gastroenterology
Manuscript ID	32205
Country	Japan

Received	2016-12-29 14:53
Peer-Review Started	2016-12-29 21:10
To Make the First Decision	2017-01-19 10:37
Return for Revision	2017-01-23 08:22
Revised	2017-02-07 18:50
Second Decision	2017-03-01 11:14
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-03-02 17:03
Articles in Press	2017-03-02 17:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-03-10 15:39
Publish the Manuscript Online	2017-03-19 18:45

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Immunology
Manuscript Type	Review
Article Title	Role of autophagy in the pathogenesis of inflammatory bowel disease
Manuscript Source	Invited Manuscript
All Author List	Tomoya Iida, Kei Onodera and Hiroshi Nakase
Funding Agency and Grant Number
Corresponding Author	Dr. Hiroshi Nakase, Department of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine, Minami 1-jo Nishi 16-chome, Chuo-ku, Sapporo, Hokkaido 060-8556, Japan. hiropynakase@gmail.com
Key Words	Autophagy; Inflammatory bowel disease; Genome-wide association study; Ulcerative colitis; Crohn’s disease
Core Tip	Recent studies provide strong evidence that the process of autophagy affects several aspects of mucosal immune responses. Autophagy is a cellular stress response that plays key roles in physiological processes. Dysfunctional autophagy is recognized as a contributing factor in many chronic inflammatory diseases, including inflammatory bowel disease (IBD). Autophagy plays multiple roles in IBD pathogenesis. Recent studies have identified susceptibility genes involved in autophagy, such as NOD2, ATG16L1, and IRGM, and active research is ongoing around the world. The aim of this review is a systematic appraisal of current literature to provide a better understanding of the role of autophagy in IBD pathogenesis.
Publish Date	2017-03-19 18:45
Citation	Iida T, Onodera K, Nakase H. Role of autophagy in the pathogenesis of inflammatory bowel disease. World J Gastroenterol 2017; 23(11): 1944-1953
URL	http://www.wjgnet.com/1007-9327/full/v23/i11/1944.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i11.1944

Full Article (PDF)	WJG-23-1944.pdf
Full Article (Word)	WJG-23-1944.doc
Manuscript File	32205-Review.docx
Answering Reviewers	32205-Answering reviewers.pdf
Audio Core Tip	32205-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	32205-Conflict-of-interest statement.pdf
Copyright License Agreement	32205-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	32205-Language certificate.pdf
Peer-review Report	32205-Peer-review(s).pdf
Scientific Misconduct Check	32205-Scientific misconduct check.pdf
Scientific Editor Work List	32205-Scientific editor work list.pdf