| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Wall shear stress in portal vein of cirrhotic patients with portal hypertension
|
| Manuscript Source |
Invited Conference Manuscripts |
| All Author List |
Wei Wei, Yan-Song Pu, Xin-Kai Wang, An Jiang, Rui Zhou, Yu Li, Qiu-Juan Zhang, Ya-Juan Wei, Bin Chen and Zong-Fang Li |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Program for Changjiang Scholars and Innovative Research Team in Universities |
PCSIRT-1171 |
| National Natural Science Foundation of China |
81270504 |
| Fundamental Research Funds for the Central Universities |
xjj20100209 |
|
| Corresponding Author |
Zong-Fang Li, MD, PhD, Professor, National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi’an Jiaotong University, No. 157 Xiwu Road, Xi’an 710004, Shaanxi Province, China. lzf2568@gmail.com |
| Key Words |
Portal hypertension; Wall shear stress; Portal vein system; Distribution; Disturbed flow |
| Core Tip |
For portal hypertension, idealized portal vein (PV) modeling showed a significantly lower wall shear stress (WSS) in both sides of the PV and the occurrence of disturbed flow in the left wall of the PV. In addition, greater risk of disturbed flow was found for smaller PV-splenic vein (SV) angle and larger superior mesenteric vein-SV angle. In patient-specific models, WSS in cirrhotic patients with portal hypertension was markedly lower than that in healthy controls and disturbed flow was more likely to occur in the portal hypertension patients. |
| Publish Date |
2017-05-15 06:16 |
| Citation |
Wei W, Pu YS, Wang XK, Jiang A, Zhou R, Li Y, Zhang QJ, Wei YJ, Chen B, Li ZF. Wall shear stress in portal vein of cirrhotic patients with portal hypertension. World J Gastroenterol 2017; 23(18): 3279-3286 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i18/3279.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i18.3279 |
