Publication Name	World Journal of Gastroenterology
Manuscript ID	32217
Country	Japan

Received	2016-12-29 15:15
Peer-Review Started	2016-12-30 15:55
To Make the First Decision	2017-01-19 10:37
Return for Revision	2017-01-23 08:23
Revised	2017-02-20 23:36
Second Decision	2017-03-09 13:18
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-03-15 09:55
Articles in Press	2017-03-15 09:55
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-03-21 18:06
Publish the Manuscript Online	2017-04-06 18:30

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Allergy
Manuscript Type	Retrospective Cohort Study
Article Title	Impact of interferon-free antivirus therapy on lipid profiles in patients with chronic hepatitis C genotype 1b
Manuscript Source	Invited Manuscript
All Author List	Daisuke Endo, Kenichi Satoh, Noritomo Shimada, Atsushi Hokari and Yoshio Aizawa
Funding Agency and Grant Number
Corresponding Author	Daisuke Endo, MD, Department of Gastroenterology and Hepatology, Internal Medicine of Jikei University Katsushika Medical Center, 6-41-2 Aoto, Katsushikaku, Tokyo 125-8506, Japan. enddai1209@yahoo.co.jp
Key Words	Chronic hepatitis C; Daclatasvir; Asunaprevir; Sofosbuvir; Ledipasvir; Total cholesterol; Low-density lipoprotein cholesterol
Core Tip	Hepatitis C virus genotype 1b (HCV1b) infection is associated with a decrease in serum cholesterol. However, little is known about the changes in lipid metabolism caused by anti-HCV therapy. Changes in serum lipid profiles were examined during and after two types of interferon-free antiviral therapy for chronic HCV1b infection. Total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol levels increased post therapy regardless of the regimen. However, the change in cholesterol during the treatment markedly varied according to the therapy protocol. These findings indicated that each anti-HCV regimen had a unique influence on lipid profiles during treatment.
Publish Date	2017-04-06 18:30
Citation	Endo D, Satoh K, Shimada N, Hokari A, Aizawa Y. Impact of interferon-free antivirus therapy on lipid profiles in patients with chronic hepatitis C genotype 1b. World J Gastroenterol 2017; 23(13): 2355-2364
URL	http://www.wjgnet.com/1007-9327/full/v23/i13/2355.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i13.2355

Full Article (PDF)	WJG-23-2355.pdf
Full Article (Word)	WJG-23-2355.doc
Manuscript File	32217-Review.docx
Answering Reviewers	32217-Answering reviewers.pdf
Audio Core Tip	32217-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	32217-Conflict-of-interest statement.pdf
Copyright License Agreement	32217-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20161228184157.docx
Institutional Review Board Approval Form or Document	32217-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	32217-Language certificate.pdf
Peer-review Report	32217-Peer-review(s).pdf
Scientific Misconduct Check	32217-Scientific misconduct check.pdf
Scientific Editor Work List	32217-Scientific editor work list.pdf