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Articles Published Processes
5/8/2017 5:42:52 PM | Browse: 996 | Download: 1829
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Received |
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2017-01-07 09:25 |
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Peer-Review Started |
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2017-01-10 14:18 |
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To Make the First Decision |
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2017-02-17 09:23 |
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Return for Revision |
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2017-02-17 16:29 |
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Revised |
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2017-03-04 02:54 |
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Second Decision |
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2017-03-13 11:00 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-03-24 10:49 |
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Articles in Press |
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2017-03-24 10:49 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-05-02 15:08 |
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Publish the Manuscript Online |
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2017-05-08 17:42 |
| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pediatrics |
| Manuscript Type |
Retrospective Study |
| Article Title |
Conversion from prolonged intravenous fentanyl infusion to enteral methadone in critically ill children
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Vijay Srinivasan, Daniel Pung and Sean P O’Neill |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Russell Raphaely Endowed Chair Funds in Critical Care Medicine, the Children’s Hospital of Philadelphia, Philadelphia, PA |
08-005894 |
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| Corresponding Author |
Vijay Srinivasan, MD, FCCM, Department of Anesthesiology and Critical Care Medicine, the Children’s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, United States. srinivasan@email.chop.edu |
| Key Words |
Methadone; Withdrawal; Children; Intensive care; Prolonged opioid infusion |
| Core Tip |
Critically ill children exposed to prolonged opioid infusions for sedation and analgesia frequently experience withdrawal symptoms when these infusions are discontinued. Conversion to intermittent opioids such as methadone may reduce such withdrawal symptoms, but published studies and guidelines vary widely in terms of dosing and timeframes for such conversions. In this pragmatic analysis of current practice in our institution, we observed wide variation in dosing conversion and timeframes. We observed that it is feasible to convert from intravenous fentanyl infusion directly to enteral methadone within a timeframe of 48 h using a methadone:fentanyl dose conversion ratio of approximately 2.5:1 to minimize withdrawal and reduce need for rescue opioids. |
| Publish Date |
2017-05-08 17:42 |
| Citation |
Srinivasan V, Pung D, O’Neill SP. Conversion from prolonged intravenous fentanyl infusion to enteral methadone in critically ill children. World J Clin Pediatr 2017; 6(2): 110-117 |
| URL |
http://www.wjgnet.com/2219-2808/full/v6/i2/110.htm |
| DOI |
http://dx.doi.org/10.5409/wjcp.v6.i2.110 |
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