Publication Name	World Journal of Cardiology
Manuscript ID	32526
Country	United States

Received	2017-01-13 09:28
Peer-Review Started	2017-01-16 08:41
To Make the First Decision	2017-05-10 17:15
Return for Revision	2017-05-11 16:48
Revised	2017-07-20 17:59
Second Decision	2017-07-28 00:07
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-08-02 20:18
Articles in Press	2017-08-02 20:18
Publication Fee Transferred	2017-08-11 05:40
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-09-13 06:34
Publish the Manuscript Online	2017-09-25 02:01

ISSN	1949-8462 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Retrospective Study
Article Title	Utility and correlation of known anticoagulation parameters in the management of pediatric ventricular assist devices
Manuscript Source	Unsolicited Manuscript
All Author List	Ajay K Bhatia, Mouhammad Yabrodi, Mallory Carroll, Silvia Bunting, Kirk Kanter, Kevin O Maher and Shriprasad R Deshpande
Funding Agency and Grant Number
Corresponding Author	Shriprasad R Deshpande, MD, Division of Pediatric Cardiology, Emory University School of Medicine, Children’s Healthcare of Atlanta, 1405, Clifton Rd NE, Atlanta, GA 30322, United States. deshpandes@kidsheart.com
Key Words	Ventricular assist device; Anticoagulation; BERLIN-EXCOR; Pediatric; Thromboelastography
Core Tip	This study suggests that while there is strong correlation between activated thromboplastin time, anti-Xa assay and R-thromboelastography values for patients requiring ventricular assist device support, there is a lack of relevant correlation between heparin dose and degree of effect. This raises concern as various guidelines continue to recommend using these parameters to titrate heparin therapy. A comprehensive strategy for appropriate anticoagulation may therefore warrant a combination of parameter monitoring and warrants further study.
Publish Date	2017-09-25 02:01
Citation	Bhatia AK, Yabrodi M, Carroll M, Bunting S, Kanter K, Maher KO, Deshpande SR. Utility and correlation of known anticoagulation parameters in the management of pediatric ventricular assist devices. World J Cardiol 2017; 9(9): 749-756
URL	http://www.wjgnet.com/1949-8462/full/v9/i9/749.htm
DOI	http://dx.doi.org/10.4330/wjc.v9.i9.749

Full Article (PDF)	WJC-9-749.pdf
Full Article (Word)	WJC-9-749.doc
Manuscript File	32526-Review.docx
Answering Reviewers	32526-Answering reviewers.pdf
Audio Core Tip	32526-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	32526-Conflict-of-interest statement.pdf
Copyright License Agreement	32526-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	32526-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	32526-Institutional review board statement.pdf
Supplementary Material	32526-Supplementary material.docx
Peer-review Report	32526-Peer-review(s).pdf
Scientific Misconduct Check	32526-Scientific misconduct check.pdf
Scientific Editor Work List	32526-Scientific editor work list.pdf