Publication Name	World Journal of Gastroenterology
Manuscript ID	32635
Country	China

Received	2017-01-18 10:49
Peer-Review Started	2017-01-19 15:39
First Decision by Editorial Office Director
Return for Revision	2017-02-27 15:30
Revised	2017-03-27 14:09
Publication Fee Transferred	2017-05-15 05:50
Second Decision by Editor	2017-05-04 17:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2017-05-09 17:09
Articles in Press	2017-05-09 17:09
Edit the Manuscript by Language Editor	2017-05-26 21:38
Typeset the Manuscript	2017-07-30 10:55
Publish the Manuscript Online	2017-08-07 09:17

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Salvianolic acid B protects hepatocytes from H2O2 injury by stabilizing the lysosomal membrane
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao-Feng Yan, Pei Zhao, Dong-Yan Ma, Yi-Lu Jiang, Jiao-Jiao Luo, Liu Liu and Xiao-Ling Wang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Funds of China 81503367 the Budget Research Project of Shanghai Education Commission 2014YSN03 the Budget Research Project of Shanghai Education Commission 2014YSN22
Corresponding Author	Xiao-Ling Wang, Department of Biology, School of basic medical science, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Pudong, Shanghai 201203, China. wangxiaoling1033@shutcm.edu.cn
Key Words	Lysosomal membrane permeabilization; Injury; Salvianolic acid B; Hepatocyte
Core Tip	Lysosomal membrane permeabilization leads to the release of luminal contents, such as proteases and protons, into the cytosol, resulting in cell death. Salvianolic acid B (Sal B), a water-soluble compound extracted from Salvia miltiorrhiza, exerts a cell protective effect by anti-oxidation. In the present study, we elucidate that Sal B protects hepatocytes from H2O2/CCl4 -induced injury/death by stabilizing the lysosomal membrane.
Publish Date	2017-08-07 09:17
Citation	Yan XF, Zhao P, Ma DY, Jiang YL, Luo JJ, Liu L, Wang XL. Salvianolic acid B protects hepatocytes from H2O2 injury by stabilizing the lysosomal membrane. World J Gastroenterol 2017; 23(29): 5333-5344
URL	http://www.wjgnet.com/1007-9327/full/v23/i29/5333.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i29.5333

Full Article (PDF)	WJG-23-5333.pdf
Full Article (Word)	WJG-23-5333.doc
Manuscript File	32635-Review.doc
Answering Reviewers	32635-Answering reviewers.docx
Audio Core Tip	32635-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	32635-Conflict-of-interest statement.pdf
Copyright License Agreement	32635-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	32635-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	32635-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	32635-Language certificate.pdf
Peer-review Report	32635-Peer-review(s).pdf
Scientific Misconduct Check	32635-Scientific misconduct check.pdf
Scientific Editor Work List	32635-Scientific editor work list.pdf