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8/7/2017 9:17:02 AM | Browse: 220 | Download: 291
Publication Name World Journal of Gastroenterology
Manuscript ID 32635
Country of Manuscript Source China
Received
2017-01-18 10:49
Peer-Review Started
2017-01-19 15:39
To Make the First Decision
2017-02-23 10:25
Return for Revision
2017-02-27 15:30
Revised
2017-03-27 14:09
Second Decision
2017-05-04 17:39
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-05-09 17:09
Articles in Press
2017-05-09 17:09
Publication Fee Transferred
2017-05-15 05:50
Edit the Manuscript by Language Editor
2017-05-26 21:38
Typeset the Manuscript
2017-07-30 10:55
Publish the Manuscript Online
2017-08-07 09:17
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title Salvianolic acid B protects hepatocytes from H2O2 injury by stabilizing the lysosomal membrane
Manuscript Source Unsolicited Manuscript
All Author List Xiao-Feng Yan, Pei Zhao, Dong-Yan Ma, Yi-Lu Jiang, Jiao-Jiao Luo, Liu Liu and Xiao-Ling Wang
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Funds of China 81503367
the Budget Research Project of Shanghai Education Commission 2014YSN03
the Budget Research Project of Shanghai Education Commission 2014YSN22
Corresponding author Xiao-Ling Wang, Department of Biology, School of basic medical science, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Pudong, Shanghai 201203, China. wangxiaoling1033@shutcm.edu.cn
Keywords Lysosomal membrane permeabilization; Injury; Salvianolic acid B; Hepatocyte
Core Tip Lysosomal membrane permeabilization leads to the release of luminal contents, such as proteases and protons, into the cytosol, resulting in cell death. Salvianolic acid B (Sal B), a water-soluble compound extracted from Salvia miltiorrhiza, exerts a cell protective effect by anti-oxidation. In the present study, we elucidate that Sal B protects hepatocytes from H2O2/CCl4 -induced injury/death by stabilizing the lysosomal membrane.
Publish Date 2017-08-07 09:17
Citation Yan XF, Zhao P, Ma DY, Jiang YL, Luo JJ, Liu L, Wang XL. Salvianolic acid B protects hepatocytes from H2O2 injury by stabilizing the lysosomal membrane. World J Gastroenterol 2017; 23(29): 5333-5344
Url http://www.wjgnet.com/1007-9327/full/v23/i29/5333.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i29.5333
Full Article (PDF) WJG-23-5333.pdf
Full Article (Word) WJG-23-5333.doc
Manuscript File 32635-Review.doc
Answering Reviewers 32635-Answering reviewers.docx
Audio Core Tip 32635-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 32635-Conflict-of-interest statement.pdf
Copyright License Agreement 32635-Copyright assignment.pdf
Data Sharing Statement 32635-Data sharing statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document 32635-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 32635-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 32635-Language certificate.pdf
Scientific Research Process 32635-Scientific research process.pdf
Peer-review Report 32635-Peer-review(s).pdf
Scientific Misconduct Check 32635-Scientific misconduct check.pdf
Scientific Editor Work List 32635-Scientific editor work list.pdf