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5/27/2017 12:33:29 AM | Browse: 125 | Download: 130
Publication Name World Journal of Gastroenterology
Manuscript ID 32644
Country of Manuscript Source Italy
Received
2017-01-18 10:23
Peer-Review Started
2017-01-19 19:40
To Make the First Decision
2017-02-09 15:03
Return for Revision
2017-02-14 11:50
Revised
2017-03-07 23:47
Second Decision
2017-04-27 17:24
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-05-04 18:26
Articles in Press
2017-05-04 18:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-05-19 02:26
Publish the Manuscript Online
2017-05-27 00:33
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7901 Stoneridge Drive, Suite 501, Pleasanton, CA 94588, USA
Website http://www.wjgnet.com
Specialty Transplantation
Manuscript Type Retrospective Cohort Study
Article Title Radiological response and inflammation scores predict tumour recurrence in patients treated with transarterial chemoembolization before liver transplantation
Manuscript Source Invited Manuscript
All Author List Daniele Nicolini, Andrea Agostini, Roberto Montalti, Federico Mocchegiani, Cinzia Mincarelli, Alessandra Mandolesi, Nicola L Robertson, Roberto Candelari, Andrea Giovagnogni and Marco Vivarelli
Funding Agency and Grant Number
Correspondence To Daniele Nicolini, MD, PhD, Division of Hepatobiliary and Transplant Surgery, Department of Experimental and Clinical Medicine, Polytechnic University of Marche, via Tronto n°10/a, 60126 Ancona, Italy. daniele.nicolini@ospedaliriuniti.marche.it
Keywords Liver transplantation; Recurrence-free survival; Hepatocellular carcinoma; Radiological response; Locoregional therapies; Inflammatory markers; Selection criteria
Core Tip The response to loco-regional therapy and biological markers appear to stratify the prognosis of hepatocellular carcinoma patients awaiting liver transplantation (LT) better than morphological criteria; however, their role in the selection scheme still needs validation. We analysed a homogeneous cohort of 70 patients treated exclusively by transarterial chemoembolization (TACE) prior to LT; the radiological response was assessed by two different enhancing methods (mRECIST and EASL criteria) that provided an accurate preoperative estimation of histological necrosis. We also demonstrated that a lack of response to TACE and a high platelet-to-lymphocyte ratio before surgery are strongly predictive of tumour recurrence, independently of the Milan criteria status at referral.
Publish Date 2017-05-27 00:33
Citation Nicolini D, Agostini A, Montalti R, Mocchegiani F, Mincarelli C, Mandolesi A, Robertson NL, Candelari R, Giovagnoni A, Vivarelli M. Radiological response and inflammation scores predict tumour recurrence in patients treated with transarterial chemoembolization before liver transplantation. World J Gastroenterol 2017; 23(20): 3690-3701
Url http://www.wjgnet.com/1007-9327/full/v23/i20/3690.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i20.3690
Full Article (PDF) WJG-23-3690.pdf
Full Article (Word) WJG-23-3690.doc
Revised Manuscript 32644-Review.docx
Peer-review Report 32644-Peer-review(s).pdf
Answering Reviewers 32644-Answering reviewers.pdf
Scientific Misconduct Check 32644-Scientific misconduct check.pdf
Scientific Editor Work List 32644-Scientific editor work list.pdf
Audio 32644-Audio core tip.m4a
Biostatistics Statement 32644-Biostatistics statement.pdf
Conflict-of-Interest Statement 32644-Conflict-of-interest statement.pdf
Copyright Assignment 32644-Copyright assignment.pdf
Data Sharing Statement 32644-Data sharing statement.pdf
Informed Consent Statement 32644-Informed consent statement.pdf
Institutional Review Board Statement 32644-Institutional review board statement.pdf
Non-Native Speakers of English 32644-Language certificate.pdf
Scientific Research Process 32644-Scientific research process.pdf