Publication Name	World Journal of Hepatology
Manuscript ID	32658
Country	Pakistan

Received	2017-01-18 20:29
Peer-Review Started	2017-01-20 20:01
To Make the First Decision	2017-03-13 10:35
Return for Revision	2017-03-16 19:06
Revised	2017-03-19 12:56
Second Decision	2017-06-08 07:24
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-06-13 04:55
Articles in Press	2017-06-13 04:55
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-07-25 09:37
Publish the Manuscript Online	2017-08-07 06:12

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Evidence-Based Medicine
Article Title	Serum cholinesterase: A predictive biomarker of hepatic reserves in chronic hepatitis D
Manuscript Source	Invited Manuscript
All Author List	Minaam Abbas and Zaigham Abbas
Funding Agency and Grant Number
Corresponding Author	Dr. Zaigham Abbas, FCPS, FRCP, Department of Medicine, Orthopedic and Medical Institute, Depot Lines, Karachi 74400, Pakistan. drzabbas@gmail.com
Key Words	Cholinesterase; Liver function; Cirrhosis; Model for Endstage Liver Disease score; Aspartate transaminase-to-platelet ratio index; Hepatitis D; Child Turcotte Pugh score; Baseline-event-anticipation score
Core Tip	Prognostic models to assess liver function in patients with chronic liver disease are used extensively in clinical settings. These systems employ multiple clinical and laboratory parameters to evaluate liver reserves and predict outcome. In our study we assessed cholinesterase as an independent predictor of hepatic reserves. We found that its values correlated strongly with Liver function tests and with the existing scoring models. Thereafter, we defined optimal cholinesterase levels corresponding to the different stages and classes of the scoring systems and hence the severity of chronic liver disease. The study’s subjects were patients suffering from cirrhosis due to hepatitis D.
Publish Date	2017-08-07 06:12
Citation	Abbas M, Abbas Z. Serum cholinesterase: a predictive biomarker of hepatic reserves in chronic hepatitis D. World J Hepatol 2017; 9(22): 967-972
URL	http://www.wjgnet.com/1948-5182/full/v9/i22/967.htm
DOI	http://dx.doi.org/10.4254/wjh.v9.i22.967

Full Article (PDF)	WJH-9-967.pdf
Full Article (Word)	WJH-9-967.doc
Manuscript File	32658-Review.docx
Answering Reviewers	32658-Answering reviewers.pdf
Audio Core Tip	32658-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	32658-Conflict-of-interest statement.pdf
Copyright License Agreement	32658-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	32658-Institutional review board statement.pdf
Peer-review Report	32658-Peer-review(s).pdf
Scientific Misconduct Check	32658-Scientific misconduct check.pdf
Scientific Editor Work List	32658-Scientific editor work list.pdf