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8/7/2017 6:12:33 AM | Browse: 938 | Download: 1622
Publication Name World Journal of Hepatology
Manuscript ID 32659
Country/Territory Singapore
Received
2017-01-18 20:31
Peer-Review Started
2017-01-20 20:02
To Make the First Decision
2017-03-13 17:46
Return for Revision
2017-03-16 19:10
Revised
2017-03-24 14:04
Second Decision
2017-06-08 07:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-06-13 04:57
Articles in Press
2017-06-13 04:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-07-27 09:01
Publish the Manuscript Online
2017-08-07 06:12
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Low serum albumin predicts early mortality in patients with severe hypoxic hepatitis
Manuscript Source Invited Manuscript
All Author List Pik-Eu Chang, Boon-Bee George Goh, Victoria Ekstrom, Ming-Liang Ong and Chee-Kiat Tan
Funding Agency and Grant Number
Corresponding Author Chee-Kiat Tan, MBBS(NUS), MRCP(UK), FRCP(Edinburgh), Associate Professor, Department of Gastroenterology and Hepatology, Singapore General Hospital, Academia, 20 College Road, Level 3, Singapore 169856, Singapore. tan.chee.kiat@singhealth.com.sg
Key Words Severe; Mortality; Albumin; Incidence; Hypoxic hepatitis; Predictors; Etiology; Prognosis
Core Tip Hypoxic hepatitis is an important cause of liver injury that is associated with a high mortality rate. We sought to evaluate the incidence, etiology and predictors of mortality of severe hypoxic hepatitis in a large tertiary-level hospital in Singapore. Our findings confirm that the prevalence and mortality rate of severe hypoxic hepatitis in Asians is consistent with previous studies. Importantly, the unique finding from our study is that low serum albumin level is an independent predictive factor for mortality in severe hypoxic hepatitis, with a five-fold increase in risk of death in patients with serum albumin less than 28 g/L.
Publish Date 2017-08-07 06:12
Citation Chang PE, Goh BBG, Ekstrom V, Ong ML, Tan CK. Low serum albumin predicts early mortality in patients with severe hypoxic hepatitis. World J Hepatol 2017; 9(22): 959-966
URL http://www.wjgnet.com/1948-5182/full/v9/i22/959.htm
DOI http://dx.doi.org/10.4254/wjh.v9.i22.959
Full Article (PDF) WJH-9-959.pdf
Full Article (Word) WJH-9-959.doc
Manuscript File 32659-Review.docx
Answering Reviewers 32659-Answering reviewers.pdf
Audio Core Tip 32659-Audio core tip.mp3
Biostatistics Review Certificate 32659-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 32659-Conflict-of-interest statement.pdf
Copyright License Agreement 32659-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) 32659-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 32659-Institutional review board statement.pdf
Peer-review Report 32659-Peer-review(s).pdf
Scientific Misconduct Check 32659-Scientific misconduct check.pdf
Scientific Editor Work List 32659-Scientific editor work list.pdf