Publication Name	World Journal of Hepatology
Manuscript ID	32726
Country	China

Received	2017-01-21 11:04
Peer-Review Started	2017-01-23 08:55
To Make the First Decision	2017-02-17 09:26
Return for Revision	2017-02-17 17:16
Revised	2017-03-03 16:20
Second Decision	2017-03-24 11:35
Accepted by Journal Editor-in-Chief	2017-03-24 12:11
Accepted by Executive Editor-in-Chief	2017-04-10 09:25
Articles in Press	2017-04-10 09:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-05-04 09:31
Publish the Manuscript Online	2017-05-08 11:13

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Surgery
Manuscript Type	Retrospective Study
Article Title	Importance of surgical margin in the outcomes of hepatocholangiocarcinoma
Manuscript Source	Invited Manuscript
All Author List	Ka Wing Ma and Kenneth Siu Ho Chok
Funding Agency and Grant Number
Corresponding Author	Kenneth Siu Ho Chok, MS, Associate Professor, Department of Surgery, the University of Hong Kong, 102 Pok Fu Lam Road, Hong Kong, China. kennethchok@gmail.com
Key Words	Hepatocholangiocarcinoma; Hepatocellular cholangiocarcinoma; Survival; Hepatectomy; Resection margin
Core Tip	A retrospective review of all patients who had undergone curative resection for hepatocholan­giocarcinoma in the last 20 years was performed in a university center. The 5-year disease-free and overall survival were 23.6% and 35.4% respectively. Various patient and disease factors were investigated with respect to their effect to disease free and overall survival using cox regression analysis. Multifocality was the only independent factor associated with disease-free survival (P < 0.001). In a subgroup of patient (n = 20) who had multifocal tumor, resection margin of ≥ 1 cm was associated with improved 1-year disease-free survival (40% vs 0%, P = 0.012).
Publish Date	2017-05-08 11:13
Citation	Ma KW, Chok KSH. Importance of surgical margin in the outcomes of hepatocholangiocarcinoma. World J Hepatol 2017; 9(13): 635-641
URL	http://www.wjgnet.com/1948-5182/full/v9/i13/635.htm
DOI	http://dx.doi.org/10.4254/wjh.v9.i13.635

Full Article (PDF)	WJH-9-635.pdf
Full Article (Word)	WJH-9-635.doc
Manuscript File	32726-Review.docx
Answering Reviewers	32726-Answering reviewers.pdf
Audio Core Tip	32726-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	32726-Conflict-of-interest statement.pdf
Copyright License Agreement	32726-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	32726-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	32726-Institutional review board statement.pdf
Peer-review Report	32726-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	32726-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	32726-Scientific misconduct check.pdf
Scientific Editor Work List	32726-Scientific editor work list.pdf