Publication Name	World Journal of Orthopedics
Manuscript ID	32790
Country	United States

Received	2017-01-23 09:04
Peer-Review Started	2017-02-02 22:50
To Make the First Decision	2017-03-27 12:00
Return for Revision	2017-03-28 17:52
Revised	2017-04-05 23:27
Second Decision	2017-04-24 17:49
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-05-15 03:59
Articles in Press	2017-05-15 03:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-06-06 02:17
Publish the Manuscript Online	2017-06-16 08:41

ISSN	2218-5836 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Orthopedics
Manuscript Type	Systematic Reviews
Article Title	Clinical application of concentrated bone marrow aspirate in orthopaedics: A systematic review
Manuscript Source	Invited Manuscript
All Author List	Arianna L Gianakos, Li Sun, Jay N Patel, Donald M Adams and Frank A Liporace
Funding Agency and Grant Number
Corresponding Author	Frank A Liporace, MD, Chairman, Division of Orthopedic Surgery, Department of Orthopedic Surgery, Jersey City Medical Center - RWJ Barnabas Health, 355 Grand Street, Jersey City, NJ 07302, United States. liporace33@gmail.com
Key Words	Concentrated bone marrow aspirate; Bone; Cartilage; Osteochondral lesion; Osteoarthritis; Tendon
Core Tip	With the widespread use of orthobiologics in everyday practice, attention must be directed to substantiate the evidence for their current use and to direct future practice guidelines. The use of concentrated bone marrow aspirate (cBMA) has become an increasingly popular alternative and adjunct in the treatment of cartilaginous lesions, bony defects, and tendinous injuries. This systematic review demonstrates the potential benefits of utilizing cBMA for the repair of different tissue types in the clinical setting. This systematic review also highlights discrepancies between the literature with regards to various methods of centrifugation, variable cell count concentrations, variable methods of application of cBMA, and the lack of standardized outcome measures.
Publish Date	2017-06-16 08:41
Citation	Gianakos AL, Sun L, Patel JN, Adams DM, Liporace FA. Clinical application of concentrated bone marrow aspirate in orthopaedics: A systematic review. World J Orthop 2017; 8(6): 491-506
URL	http://www.wjgnet.com/2218-5836/full/v8/i6/491.htm
DOI	http://dx.doi.org/10.5312/wjo.v8.i6.491

Full Article (PDF)	WJO-8-491.pdf
Full Article (Word)	WJO-8-491.doc
Manuscript File	32790-Review.docx
Answering Reviewers	32790-Answering reviewers.pdf
Audio Core Tip	32790-Audio core tip.m4a
Biostatistics Review Certificate	32790-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	32790-Conflict-of-interest statement.pdf
Copyright License Agreement	32790-Copyright assignment.pdf
Supplementary Material	Supplementary_Material_20170123042819.xlsx
Peer-review Report	32790-Peer-review(s).pdf
Scientific Misconduct Check	32790-Scientific misconduct check.pdf
Scientific Editor Work List	32790-Scientific editor work list.pdf