Publication Name	World Journal of Gastroenterology
Manuscript ID	32840
Country	United States

Received	2017-01-29 16:58
Peer-Review Started	2017-02-01 20:09
To Make the First Decision	2017-03-03 10:08
Return for Revision	2017-03-06 17:21
Revised	2017-05-18 05:51
Second Decision	2017-06-06 00:41
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-06-12 08:40
Articles in Press	2017-06-12 08:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-06-26 09:04
Publish the Manuscript Online	2017-07-07 11:41

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Transplantation
Manuscript Type	Basic Study
Article Title	Treatment with dimethyl fumarate ameliorates liver ischemia/reperfusion injury
Manuscript Source	Invited Manuscript
All Author List	Chie Takasu, Nosratola D Vaziri, Shiri Li, Lourdes Robles, Kelly Vo, Mizuki Takasu, Christine Pham, Seyed H Farzaneh, Mitsuo Shimada, Michael J Stamos and Hirohito Ichii
Funding Agency and Grant Number
Corresponding Author	Hirohito Ichii, MD, PhD, Department of Surgery, University of California, Irvine, 333 City Boulevard West Suite 1205, Orange, CA 92868, United States. hichii@uci.edu
Key Words	Inflammation; Reactive oxidative stress; Nrf2; Ischemia; Dimethyl fumarate; Liver
Core Tip	In this study, we reveal that (1) administration of dimethyl fumarate (DMF) significantly reduced tissue damage, improved liver function; and (2) DMF attenuated oxidative stress and inflammation, and raised anti-oxidant status in rats with hepatic ischemia/reperfusion injury (I/RI). These findings suggest that DMF treatment could be a promising strategy to improve clinical outcome in patients with liver I/RI.
Publish Date	2017-07-07 11:41
Citation	Takasu C, Vaziri ND, Li S, Robles L, Vo K, Takasu M, Pham C, Farzaneh SH, Shimada M, Stamos MJ, Ichii H. Treatment with dimethyl fumarate ameliorates liver ischemia/reperfusion injury. World J Gastroenterol 2017; 23(25): 4508-4516
URL	http://www.wjgnet.com/1007-9327/full/v23/i25/4508.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i25.4508

Full Article (PDF)	WJG-23-4508.pdf
Full Article (Word)	WJG-23-4508.doc
Manuscript File	32840-Review.docx
Audio Core Tip	32840-Audio core tip.mp3
Biostatistics Review Certificate	32840-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	32840-Conflict-of-interest statement.pdf
Copyright License Agreement	32840-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	32840-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	32840-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	32840-Language certificate.pdf
Peer-review Report	32840-Peer-review(s).pdf
Scientific Misconduct Check	32840-Scientific misconduct check.pdf
Scientific Editor Work List	32840-Scientific editor work list.pdf