Publication Name	World Journal of Critical Care Medicine
Manuscript ID	32973
Country	Brazil

Received	2017-02-03 16:07
Peer-Review Started	2017-02-08 15:07
To Make the First Decision	2017-04-17 09:27
Return for Revision	2017-04-17 10:42
Revised	2017-04-27 12:07
Second Decision	2017-06-29 08:27
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-07-10 02:50
Articles in Press	2017-07-10 02:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-07-26 07:17
Publish the Manuscript Online	2017-08-02 08:20

ISSN	2220-3141(online)
Open Access
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Critical Care Medicine
Manuscript Type	Review
Article Title	Immunomodulatory effects of anesthetics in obese patients
Manuscript Source	Invited Manuscript
All Author List	Luciana Boavista Barros Heil, Pedro Leme Silva, Paolo Pelosi and Patricia Rieken Macedo Rocco
Funding Agency and Grant Number	Funding Agency Grant Number Brazilian Council for Scientific and Technological Development (CNPq) Carlos Chagas Filho Rio de Janeiro State Foundation (FAPERJ) Department of Science and Technology (DECIT) Brazilian Ministry of Health; and Coordination for the Improvement of Higher Level Personnel (CAPES)
Corresponding Author	Patricia Rieken Macedo Rocco, MD, PhD, Professor, Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Centro de Ciências da Saúde, Avenida Carlos Chagas Filho, 373, Bloco G-014, Ilha do Fundão, Rio de Janeiro 21941-902, Brazil. prmrocco@biof.ufrj.br
Key Words	Anesthesia; Immune system; Perioperative care; Obesity; Inflammation
Core Tip	Anesthetic agents have been studied not only for their effects on anesthesia and analgesia, but also their action on the lungs and immune system. Obesity is associated with a chronic state of low-grade systemic inflammation, and may predispose to development of comorbidities. Although efforts have been made to develop guidelines for anesthesia in obesity, to date, no ideal drug combination has been found. Optimization of the immunomodulatory properties of anesthetic agents may enable perioperative modulation of inflammatory response in obese patients and improve postoperative outcomes.
Publish Date	2017-08-02 08:20
Citation	Heil LBB, Silva PL, Pelosi P, Rocco PRM. Immunomodulatory effects of anesthetics in obese patients. World J Crit Care Med 2017; 6(3): 140-152
URL	http://www.wjgnet.com/2220-3141/full/v6/i3/140.htm
DOI	http://dx.doi.org/10.5492/wjccm.v6.i3.140

Full Article (PDF)	WJCCM-6-140.pdf
Full Article (Word)	WJCCM-6-140.doc
Manuscript File	32973-Review.docx
Answering Reviewers	32973-Answering reviewers.pdf
Audio Core Tip	32973-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	32973-Conflict-of-interest statement.pdf
Copyright License Agreement	32973-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	32973-Grant application form(s).pdf
Peer-review Report	32973-Peer-review(s).pdf
Scientific Misconduct Check	32973-Scientific misconduct check.pdf
Scientific Editor Work List	32973-Scientific editor work list.pdf