Publication Name	World Journal of Hepatology
Manuscript ID	33014
Country	United States

Received	2017-02-04 09:34
Peer-Review Started	2017-02-12 15:44
To Make the First Decision	2017-03-08 09:39
Return for Revision	2017-03-09 16:34
Revised	2017-03-24 01:56
Second Decision	2017-03-29 10:10
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-04-10 09:04
Articles in Press	2017-04-10 09:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-05-03 16:11
Publish the Manuscript Online	2017-05-08 11:13

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an inhouse editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Management of centrally located hepatocellular carcinoma: Update 2016
Manuscript Source	Invited Manuscript
All Author List	Wei-Bo Yu, Andrew Rao, Victor Vu, Lily Xu, Jian-Yu Rao and Jian-Xiong Wu
Funding Agency and Grant Number
Corresponding Author	Jian-Xiong Wu, MD, Professor, Chief, Department of Hepatobiliary Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 17 Panjiayuan Nanli, Beijing 100021, China. dr.wujx@hotmail.com
Key Words	Centrally located hepatocellular carcinoma; Hepatectomy; Combined treatment; Hepatic vascular occlusion
Core Tip	Centrally located hepatocellular carcinoma (HCC) is situated in the deeper portions of the liver and adjoins main vascular structures. Due to this special location, the management of this group of patients is challenging. Low resection rates and high recurrence rates are two major problems that urgently need to be resolved. This review summarizes the evolution of our understanding for centrally located HCC and the development of disease management, and explores the possible strategies to improve overall patient survival.
Publish Date	2017-05-08 11:13
Citation	Yu WB, Rao A, Vu V, Xu L, Rao JY, Wu JX. Management of centrally located hepatocellular carcinoma: Update 2016. World J Hepatol 2017; 9(13): 627-634
URL	http://www.wjgnet.com/1948-5182/full/v9/i13/627.htm
DOI	http://dx.doi.org/10.4254/wjh.v9.i13.627

Full Article (PDF)	WJH-9-627.pdf
Full Article (Word)	WJH-9-627.doc
Manuscript File	33014-Review.docx
Answering Reviewers	33014-Answering reviewers.pdf
Audio Core Tip	33014-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	33014-Conflict-of-interest statement.pdf
Copyright License Agreement	33014-Copyright assignment.pdf
Peer-review Report	33014-Peer-review(s).pdf
Scientific Misconduct Check	33014-Scientific misconduct check.pdf
Scientific Editor Work List	33014-Scientific editor work list.pdf