Publication Name	World Journal of Gastroenterology
Manuscript ID	33198
Country	Switzerland

Received	2017-02-07 16:12
Peer-Review Started	2017-02-10 09:55
To Make the First Decision	2017-03-03 09:32
Return for Revision	2017-03-07 10:42
Revised	2017-03-29 04:38
Second Decision	2017-04-27 18:11
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-05-04 18:30
Articles in Press	2017-05-04 18:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-05-11 21:01
Publish the Manuscript Online	2017-05-27 00:33

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Pediatrics
Manuscript Type	Basic Study
Article Title	Urinary metabolic insights into host-gut microbial interactions in healthy and IBD children
Manuscript Source	Invited Manuscript
All Author List	Francois-Pierre Martin, Ming-Ming Su, Guo-Xiang Xie, Seu Ping Guiraud, Martin Kussmann, Jean-Philippe Godin, Wei Jia and Andreas Nydegger
Funding Agency and Grant Number	Funding Agency Grant Number Swiss National Science Foundation 32003B_135466
Corresponding Author	François-Pierre Martin, PhD, Nestle Institute of Health Sciences, 1015 Lausanne, Switzerland. francois-pierre.martin@rd.nestle.com
Key Words	Pediatric; Metabolism; Phenotype; Growth; Inflammatory bowel disease; Crohn’s disease; Ulcerative colitis
Core Tip	Despite the limited number of subjects, the longitudinal experimental design with a healthy reference group reveals insights into childhood metabolic status in relation to growth and disease. Metabolite profiling of urine samples collected non-invasively enables identification and monitoring of biochemical signatures linked to metabolic and nutritional requirements in pediatric populations with inflammatory bowel disease (IBD). In the present study, a distinct biochemical process related to glutathione, glycine and bile acid metabolism distinguished children with IBD from healthy matched controls.
Publish Date	2017-05-27 00:33
Citation	Martin FP, Su MM, Xie GX, Guiraud SP, Kussmann M, Godin JP, Jia W, Nydegger A. Urinary metabolic insights into host-gut microbial interactions in healthy and IBD children. World J Gastroenterol 2017; 23(20): 3643-3654
URL	http://www.wjgnet.com/1007-9327/full/v23/i20/3643.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i20.3643

Full Article (PDF)	WJG-23-3643.pdf
Full Article (Word)	WJG-23-3643.doc
Manuscript File	33198-Review.docx
Answering Reviewers	33198-Answering reviewers.pdf
Audio Core Tip	33198-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	33198-Conflict-of-interest statement.pdf
Copyright License Agreement	33198-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	33198-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20170129011421.pdf
Institutional Review Board Approval Form or Document	33198-Institutional review board statement.pdf
Peer-review Report	33198-Peer-review(s).pdf
Scientific Misconduct Check	33198-Scientific misconduct check.pdf
Scientific Editor Work List	33198-Scientific editor work list.pdf