Publication Name	World Journal of Psychiatry
Manuscript ID	33281
Country	Japan

Received	2017-02-08 10:57
Peer-Review Started	2017-02-12 22:12
To Make the First Decision	2017-03-27 11:23
Return for Revision	2017-03-28 16:42
Revised	2017-04-10 18:56
Second Decision	2017-04-24 17:53
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-05-05 16:36
Articles in Press	2017-05-05 16:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-06-08 06:57
Publish the Manuscript Online	2017-06-22 11:06

ISSN	2220-3206 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Psychiatry
Manuscript Type	Observational Study
Article Title	Three-dimensional stereotactic surface projection in the statistical analysis of single photon emission computed tomography data for distinguishing between Alzheimer’s disease and depression
Manuscript Source	Invited Manuscript
All Author List	Eiji Kirino
Funding Agency and Grant Number
Corresponding Author	Eiji Kirino, MD, PhD, Department of Psychiatry, Juntendo University Shizuoka Hospital, 1129 Nagaoka, Izunokuni-shi, Shizuoka 410-2211, Japan. ekirino@juntendo.ac.jp
Key Words	Alzheimer’s disease; Three-dimensional stereotactic surface projection; Single photon emission computed tomography; Pseudo-dementia; Depression
Core Tip	The present study aimed to evaluate whether statistical analysis of single photon emission computed tomography images by three-dimensional stereotactic surface projection (3D-SSP) is useful for distinguishing between Alzheimer’s disease (AD) and depression. The Minimal Mental State Examination, the Hamilton Rating Scale for Depression, and Clinical Global Impression-Severity scale findings correlated significantly with the Z-scores of AD-associated and depression-associated regions as determined using 3D-SSP analysis. Furthermore, factor analysis identified three significant factors: Factor 1, a tendency for AD; Factor 2, a tendency for pseudo-dementia; and Factor 3, a depressive tendency.
Publish Date	2017-06-22 11:06
Citation	Kirino E. Three-dimensional stereotactic surface projection in the statistical analysis of single photon emission computed tomography data for distinguishing between Alzheimer’s disease and depression. World J Psychiatr 2017; 7(2): 121-127
URL	http://www.wjgnet.com/2220-3206/full/v7/i2/121.htm
DOI	http://dx.doi.org/10.5498/wjp.v7.i2.121

Full Article (PDF)	WJP-7-121.pdf
Full Article (Word)	WJP-7-121.doc
Manuscript File	33281-Review.docx
Answering Reviewers	33281-Answering reviewers.pdf
Audio Core Tip	33281-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	33281-Conflict-of-interest statement.pdf
Copyright License Agreement	33281-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	33281-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	33281-Institutional review board statement.pdf
Peer-review Report	33281-Peer-review(s).pdf
Scientific Misconduct Check	33281-Scientific misconduct check.pdf
Scientific Editor Work List	33281-Scientific editor work list.pdf