Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	33296
Country	Australia

Received	2017-02-08 10:35
Peer-Review Started	2017-02-08 14:46
To Make the First Decision	2017-05-08 15:34
Return for Revision	2017-05-16 08:25
Revised	2017-06-26 17:36
Second Decision	2017-08-10 03:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-08-17 03:03
Articles in Press	2017-08-17 03:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-09-21 03:04
Publish the Manuscript Online	2017-10-13 01:26

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Review
Article Title	Ampullary cancer of intestinal origin and duodenal cancer - A logical clinical and therapeutic subgroup in periampullary cancer
Manuscript Source	Invited Manuscript
All Author List	Manju D Chandrasegaram, Anthony J Gill, Jas Samra, Tim Price, John Chen, Jonathan Fawcett and Neil D Merrett
Funding Agency and Grant Number
Corresponding Author	Manju D Chandrasegaram, The Prince Charles Hospital, Rode Road, Chermside, Queensland 4032, Australia. m.chandrasegaram@uq.edu.au
Key Words	Periampullary cancer; Pancreatobiliary subtype; Intestinal subtype; Ampullary cancer; Duodenal cancer; Epidermal growth factor receptor; Pancreatic cancer; Chemotherapy; Pancreaticoduodenectomy; KRAS
Core Tip	Periampullary cancers include pancreatic, ampullary, bile duct and duodenal cancers. Pancreatic cancer is the most common cancer resected with a pancreaticoduodenectomy followed by ampullary, bile duct and duodenal cancer. Patients with resected duodenal and ampullary cancers have better prognosis compared to pancreatic cancer. Ampullary cancers can be subdivided into intestinal or pancreatobiliary subtype cancers with histomolecular staining. Histomolecular profiling is superior to anatomic location in prognosticating survival. Ampullary cancers of intestinal subtype and duodenal cancers are similar in their intestinal origin and form a logical clinical and therapeutic subgroup. They respond to 5-FU based chemotherapeutic regimens such as capecitabine-oxaliplatin.
Publish Date	2017-10-13 01:26
Citation	Chandrasegaram MD, Gill AJ, Samra J, Price T, Chen J, Fawcett J, Merrett ND. Ampullary cancer of intestinal origin and duodenal cancer - A logical clinical and therapeutic subgroup in periampullary cancer. World J Gastrointest Oncol 2017; 9(10): 407-415
URL	http://www.wjgnet.com/1948-5204/full/v9/i10/407.htm
DOI	http://dx.doi.org/10.4251/wjgo.v9.i10.407

Full Article (PDF)	WJGO-9-407.pdf
Full Article (Word)	WJGO-9-407.doc
Manuscript File	33296-Revew.docx
Answering Reviewers	33296-Answering reviewers.pdf
Audio Core Tip	33296-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	33296-Conflict-of-interest statement.pdf
Copyright License Agreement	33296-Copyright assignment.pdf
Peer-review Report	33296-Peer-review(s).pdf
Scientific Misconduct Check	33296-Scientific misconduct check.pdf
Scientific Editor Work List	33296-Scientific editor work list.pdf