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7/28/2017 8:16:18 AM | Browse: 1026 | Download: 1203
Publication Name World Journal of Gastroenterology
Manuscript ID 33528
Country/Territory Norway
Received
2017-02-14 08:27
Peer-Review Started
2017-02-16 20:08
To Make the First Decision
2017-04-05 17:18
Return for Revision
2017-04-06 09:49
Revised
2017-04-15 23:29
Second Decision
2017-07-06 07:15
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-07-12 06:04
Articles in Press
2017-07-12 06:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-07-19 02:38
Publish the Manuscript Online
2017-07-28 08:16
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Gastrointestinal neuroendocrine peptides/amines in inflammatory bowel disease
Manuscript Source Invited Manuscript
All Author List Magdy El-Salhy, Tefera Solomon, Trygve Hausken, Odd Helge Gilja and Jan Gunnar Hatlebakk
Funding Agency and Grant Number
Corresponding Author Magdy El-Salhy, Professor, Division of Gastroenterology, Department of Medicine, Stord Hospital, Box 4000, Stord 5409, Norway. magdy.el-salhy@helse-fonna.no
Key Words Enteric nervous system; Enteroendocrine cells; Immune cells; Inflammatory bowel disease; Musashi-1; Neurogenin 3; Stem cells
Core Tip Approximately 80% of the body immune cells (IC) are localized in the gastrointestinal (GI) tract close to the GI neuroendocrine regulatory system (NES). Many IC express GI neuroendocrine peptides/amines (NEPA) and possess receptors to several NEPA. Several GI NEPA are abnormal during active inflammatory bowel disease (IBD) in both patients and animal models of IBD. The changes in the GI NEPA are correlated with those of the IC during the inflammatory process. Studying the interactions between the GI NES and the immune system in IBD may improve our understanding of the pathophysiology of IBD and provide us with new tools for treatment.
Publish Date 2017-07-28 08:16
Citation El-Salhy M, Solomon T, Hausken T, Gilja OH, Hatlebakk JG. Gastrointestinal neuroendocrine peptides/amines in inflammatory bowel disease. World J Gastroenterol 2017; 23(28): 5068-5085
URL http://www.wjgnet.com/1007-9327/full/v23/i28/5068.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i28.5068
Full Article (PDF) WJG-23-5068.pdf
Full Article (Word) WJG-23-5068.doc
Manuscript File 33528-Review.doc
Answering Reviewers 33528-Answering reviewers.pdf
Audio Core Tip 33528-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 33528-Conflict-of-interest statement.pdf
Copyright License Agreement 33528-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 33528-Language certificate.pdf
Supplementary Material 33528_Permission.pdf
Peer-review Report 33528-Peer-review(s).pdf
Scientific Misconduct Check 33528-Scientific misconduct check.pdf
Scientific Editor Work List 33528-Scientific editor work list.pdf