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Articles Published Processes
5/27/2017 12:33:29 AM | Browse: 1098 | Download: 2023
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Received |
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2017-02-16 09:22 |
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Peer-Review Started |
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2017-02-16 10:15 |
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To Make the First Decision |
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2017-03-14 08:32 |
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Return for Revision |
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2017-03-14 11:25 |
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Revised |
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2017-03-27 16:28 |
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Second Decision |
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2017-04-27 17:26 |
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Accepted by Journal Editor-in-Chief |
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2017-04-27 22:21 |
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Accepted by Executive Editor-in-Chief |
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2017-05-04 18:24 |
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Articles in Press |
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2017-05-04 18:24 |
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Publication Fee Transferred |
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2017-05-05 14:22 |
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Edit the Manuscript by Language Editor |
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2017-05-10 18:08 |
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Typeset the Manuscript |
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2017-05-17 02:56 |
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Publish the Manuscript Online |
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2017-05-27 00:33 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Prospective Study |
| Article Title |
Clinical significance of expression of proliferating cell nuclear antigen and E-cadherin in gastric carcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Lin Hu, Hong-Lang Li, Wei-Feng Li, Jun-Min Chen, Jian-Tao Yang, Jun-Jing Gu and Lin Xin |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81360330 |
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| Corresponding Author |
Hong-lang Li, MD, Chief physician, Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, East Lake District, Nanchang 330006, Jiangxi Province,
China. lihonglang6802@163.com |
| Key Words |
proliferating cell nuclear antigen; E-cadherin; Gastric cancer; Gastric mucosa |
| Core Tip |
The expression of proliferating cell nuclear antigen (PCNA) and E-cadherin was detected by immunohistochemistry in gastric tissues of 186 patients. During the transition of normal gastric mucosa to gastric cancer, the PCNA labeling index gradually increased, while the E-cadherin labeling index gradually decreased (P < 0.05). There was a negative correlation between the expression of PCNA and E-cadherin in gastric carcinoma. High T stage and positive PCNA expression were risk factors for the prognosis of patients with gastric cancer (RR > 1), while the positive expression of E-cadherin was a protective factor (RR < 1). Combined detection of PCNA and E-cadherin can improve the accuracy of assessing the prognosis of patients with gastric cancer. |
| Publish Date |
2017-05-27 00:33 |
| Citation |
Hu l, Li Hl, Li Wf, Chen Jm, Yang Jt, Gu Jj, Xin l. Clinical significance of expression of proliferating cell nuclear antigen and E-cadherin in gastric carcinoma. World J Gastroenterol 2017; 23(20): 3721-3729 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i20/3721.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i20.3721 |
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