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Articles Published Processes
8/19/2017 11:33:54 AM | Browse: 1019 | Download: 2280
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Received |
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2017-02-16 09:02 |
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Peer-Review Started |
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2017-02-16 17:22 |
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To Make the First Decision |
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2017-03-03 11:12 |
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Return for Revision |
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2017-03-03 11:26 |
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Revised |
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2017-03-30 03:54 |
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Second Decision |
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2017-04-14 17:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-04-21 15:20 |
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Articles in Press |
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2017-04-21 15:20 |
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Publication Fee Transferred |
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2017-04-27 10:58 |
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Edit the Manuscript by Language Editor |
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2017-05-21 10:39 |
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Typeset the Manuscript |
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2017-08-09 09:09 |
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Publish the Manuscript Online |
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2017-08-19 11:33 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Schistosoma japonicum attenuates dextran sodium sulfate-induced colitis in mice via reduction of endoplasmic reticulum stress
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ya Liu, Qing Ye, Yulan Liu, Jian Kang, Yan Chen and Weiguo Dong |
| Funding Agency and Grant Number |
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| Corresponding Author |
Dong WG, MD, PhD, Department of Gastroenterology, Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Jiefang Road 238, Wuhan 430060, Hubei Province, China. dwg@whu.edu.cn |
| Key Words |
Endoplasmic reticulum stress; Schistosoma japonicum; Colitis |
| Core Tip |
Schistosoma (S.) japonicum has been demonstrated to participate in the development of colitis in animal experiments as well as clinical trials. However, the effects of Schistosoma infection on colitis and the underlying mechanism are still elusive. Here, we studied the effects of exposure to S. japonicum cercariae on dextran sodium sulfate (DSS)-induced colitis. We found that S. japonicum attenuated DSS-induced colitis in mice by reducing inflammatory response and apoptosis in colon tissues. Besides Th1/Th2/Th17 pathway and nuclear factor-kappa B pathway, endoplasmic reticulum stress played an important role in the preventive effects of parasite infection on DSS-induced colitis. |
| Publish Date |
2017-08-19 11:33 |
| Citation |
Liu Y, Ye Q, Liu YL, Kang J, Chen Y, Dong WG. Schistosoma japonicum attenuates dextran sodium sulfate-induced colitis in mice via reduction of endoplasmic reticulum stress. World J Gastroenterol 2017; 23(31): 5700-5712 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i31/5700.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i31.5700 |
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