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8/19/2017 11:33:54 AM | Browse: 882 | Download: 1794
Publication Name World Journal of Gastroenterology
Manuscript ID 33558
Country China
Received
2017-02-16 09:02
Peer-Review Started
2017-02-16 17:22
To Make the First Decision
2017-03-03 11:12
Return for Revision
2017-03-03 11:26
Revised
2017-03-30 03:54
Second Decision
2017-04-14 17:37
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-04-21 15:20
Articles in Press
2017-04-21 15:20
Publication Fee Transferred
2017-04-27 10:58
Edit the Manuscript by Language Editor
2017-05-21 10:39
Typeset the Manuscript
2017-08-09 09:09
Publish the Manuscript Online
2017-08-19 11:33
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Schistosoma japonicum attenuates dextran sodium sulfate-induced colitis in mice via reduction of endoplasmic reticulum stress
Manuscript Source Unsolicited Manuscript
All Author List Ya Liu, Qing Ye, Yulan Liu, Jian Kang, Yan Chen and Weiguo Dong
Funding Agency and Grant Number
Corresponding Author Dong WG, MD, PhD, Department of Gastroenterology, Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Jiefang Road 238, Wuhan 430060, Hubei Province, China. dwg@whu.edu.cn
Key Words Endoplasmic reticulum stress; Schistosoma japonicum; Colitis
Core Tip Schistosoma (S.) japonicum has been demon­strated to participate in the development of colitis in animal experiments as well as clinical trials. However, the effects of Schistosoma infection on colitis and the underlying mechanism are still elusive. Here, we studied the effects of exposure to S. japonicum cercariae on dextran sodium sulfate (DSS)-induced colitis. We found that S. japonicum attenuated DSS-induced colitis in mice by reducing inflammatory response and apoptosis in colon tissues. Besides Th1/Th2/Th17 pathway and nuclear factor-kappa B pathway, endoplasmic reticulum stress played an important role in the preventive effects of parasite infection on DSS-induced colitis.
Publish Date 2017-08-19 11:33
Citation Liu Y, Ye Q, Liu YL, Kang J, Chen Y, Dong WG. Schistosoma japonicum attenuates dextran sodium sulfate-induced colitis in mice via reduction of endoplasmic reticulum stress. World J Gastroenterol 2017; 23(31): 5700-5712
URL http://www.wjgnet.com/1007-9327/full/v23/i31/5700.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i31.5700
Full Article (PDF) WJG-23-5700.pdf
Full Article (Word) WJG-23-5700.doc
Manuscript File 33558-Review.doc
Answering Reviewers 33558-Answering reviewers.pdf
Audio Core Tip 33558-Audio core tip.wma
Biostatistics Review Certificate 33558-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 33558-Conflict-of-interest statement.pdf
Copyright License Agreement 33558-Copyright assignment.docx
Signed Informed Consent Form(s) or Document(s) 33558-Informed consent statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document 33558-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 33558-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 33558-Language certificate.docx
Supplementary Material 33558-figures.pptx
Peer-review Report 33558-Peer-review(s).pdf
Scientific Misconduct Check 33558-Scientific misconduct check.pdf
Scientific Editor Work List 33558-Scientific editor work list.pdf