Publication Name	World Journal of Gastroenterology
Manuscript ID	33631
Country	Japan

Received	2017-02-22 09:22
Peer-Review Started	2017-02-22 17:18
To Make the First Decision	2017-06-05 00:30
Return for Revision	2017-06-10 11:44
Revised	2017-06-22 13:31
Second Decision	2017-07-21 07:56
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-07-24 08:00
Articles in Press	2017-07-24 08:00
Publication Fee Transferred	2017-08-04 08:37
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-08-14 03:11
Publish the Manuscript Online	2017-08-19 11:33

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Tegafur-uracil-induced rapid development of advanced hepatic fibrosis
Manuscript Source	Unsolicited Manuscript
All Author List	Shuya Honda, Koji Sawada, Takumu Hasebe, Shunsuke Nakajima, Mikihiro Fujiya and Toshikatsu Okumura
ORCID	Author(s) ORCID Number Koji Sawada http://orcid.org/0000-0002-9708-4786
Funding Agency and Grant Number
Corresponding Author	Koji Sawada, MD, PhD, Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, 2-1 Midorigaoka-higashi, Asahikawa, Hokkaido 078-8510, Japan. k-sawada@asahikawa-med.ac.jp
Key Words	Tegafur-uracil; Drug-induced liver injury; Hepatic fibrosis; Portal hypertension; Non-invasive assessment
Core Tip	This case report presents a rapid development of hepatic fibrosis induced by tegafur-uracil and the usefulness of a non-invasive assessment of hepatic fibrosis. Tegafur-uracil is often administered in patients with various cancers; therefore, when liver dysfunction progresses in patients treated with tegafur-uracil, the development of hepatic fibrosis should be considered, even for short-term administration.
Publish Date	2017-08-19 11:33
Citation	Honda S, Sawada K, Hasebe T, Nakajima S, Fujiya M, Okumura T. Tegafur-uracil-induced rapid development of advanced hepatic fibrosis. World J Gastroenterol 2017; 23(31): 5823-5828
URL	http://www.wjgnet.com/1007-9327/full/v23/i31/5823.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i31.5823

Full Article (PDF)	WJG-23-5823.pdf
Full Article (Word)	WJG-23-5823.doc
Manuscript File	33631-Review.docx
Answering Reviewers	33631-Answering reviewers.pdf
Audio Core Tip	33631-Audio core tip.wav
Conflict-of-Interest Disclosure Form	33631-Conflict-of-interest statement.pdf
Copyright License Agreement	33631-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	33631-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	33631-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	33631-Language certificate.pdf
Peer-review Report	33631-Peer-review(s).pdf
Scientific Misconduct Check	33631-Scientific misconduct check.pdf
Scientific Editor Work List	33631-Scientific editor work list.pdf