Publication Name	World Journal of Hepatology
Manuscript ID	33724
Country	United States

Received	2017-02-27 11:05
Peer-Review Started	2017-02-28 15:52
To Make the First Decision	2017-04-17 09:14
Return for Revision	2017-04-18 15:00
Revised	2017-04-29 15:19
Second Decision	2017-05-11 13:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-05-19 05:40
Articles in Press	2017-05-19 05:40
Publication Fee Transferred	2017-06-21 13:28
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-07-16 13:18
Publish the Manuscript Online	2017-08-07 06:12

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Extrahepatic metastasis of hepatocellular carcinoma to the paravertebral muscle: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Kazuhiro Takahashi, Krishna G Putchakayala, Mohamed Safwan and Dean Y Kim
Funding Agency and Grant Number
Corresponding Author	Dean Y Kim, MD, Transplant and Hepatobiliary Surgery, Henry Ford Hospital, 2790 West Grand Boulevard, Detroit, MI 48202, United States. dkim3@hfhs.org
Key Words	Hepatocellular carcinoma; Skeletal muscle; Paravertebral muscle; Extrahepatic metastasis; Stereo­tactic hypo-fractionated image guided radiation therapy; Hepatitis B virus
Core Tip	Extrahepatic metastases (EHM) of hepato­cellular carcinoma (HCC) to skeletal muscle are extre­mely rare. We describe the first case of HCC with EHM to the paravertebral muscle, in which stability of disease was achieved using stereotactic hypo-fractionated image-guided radiation therapy. A literature review revealed the strong relationship between hepatitis B viral infection and EHM. This case highlights the impor­tance of early detection of viral infection and initiation of anti-viral therapy to decrease recurrence of HCC and prevent EHM.
Publish Date	2017-08-07 06:12
Citation	Takahashi K, Putchakayala KG, Safwan M, Kim DY. Extrahepatic metastasis of hepatocellular carcinoma to the paravertebral muscle: A case report. World J Hepatol 2017; 9(22): 973-978
URL	http://www.wjgnet.com/1948-5182/full/v9/i22/973.htm
DOI	http://dx.doi.org/10.4254/wjh.v9.i22.973

Full Article (PDF)	WJH-9-973.pdf
Full Article (Word)	WJH-9-973.doc
Manuscript File	33724-Review.doc
Answering Reviewers	33724-Answering reviewers.pdf
Audio Core Tip	33724-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	33724-Conflict-of-interest statement.pdf
Copyright License Agreement	33724-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	33724-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	33724-Language certificate.pdf
Peer-review Report	33724-Peer-review(s).pdf
Scientific Misconduct Check	33724-Scientific misconduct check.pdf
Scientific Editor Work List	33724-Scientific editor work list.pdf