Publication Name	World Journal of Gastroenterology
Manuscript ID	33771
Country	Portugal

Received	2017-03-01 08:27
Peer-Review Started	2017-03-03 17:11
To Make the First Decision	2017-06-08 00:28
Return for Revision	2017-06-13 03:27
Revised	2017-06-22 19:11
Second Decision	2017-07-11 05:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-07-12 06:59
Articles in Press	2017-07-12 06:59
Publication Fee Transferred	2017-08-14 02:40
Edit the Manuscript by Language Editor	2017-08-30 01:08
Typeset the Manuscript	2017-09-08 01:29
Publish the Manuscript Online	2017-09-21 07:51

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Prospective Study
Article Title	Fecal markers levels as predictors of the need for endoscopic balloon dilation in Crohn´s disease patients with anastomotic strictures
Manuscript Source	Unsolicited Manuscript
All Author List	Susana Lopes, Patrícia Andrade, Eduardo Rodrigues-Pinto, Joana Afonso, Fernando Magro and Guilherme Macedo
Funding Agency and Grant Number
Corresponding Author	Guilherme Macedo, PhD, Department of Gastroenterology, Centro Hospitalar São João, Alameda Professor, Hernani Monteiro, Porto 4200-319, Portugal. guilherme.macedo@hsjoao.min-saude.pt
Key Words	Crohn's disease; Anastomotic strictures; Endoscopic balloon dilation; Fecal markers; Postoperative recurrence
Core Tip	This longitudinal study evaluated the accuracy of fecal calprotectin (FC) and fecal lactoferrin (FL) to predict disease recurrence in postoperative Crohn’s disease asymptomatic patients with an anastomotic stricture. FC and FL levels accurately predicted endoscopic recurrence in the presence of anastomotic stricture and thus may guide the need for endoscopic balloon dilation (EBD) in this context. A normal value of fecal markers can reassure clinicians and be safely used to avoid balloon dilation if we only aim to diagnose recurrence. A high value of fecal markers has a high likelihood of recurrence so EBD should be performed in order to provide adequate endoscopic therapy and adjust or optimize medical therapy.
Publish Date	2017-09-21 07:51
Citation	Lopes S, Andrade P, Rodrigues-Pinto E, Afonso J, Macedo G, Magro F. Fecal marker levels as predictors of need for endoscopic balloon dilation in Crohn´s disease patients with anastomotic strictures. World J Gastroenterol 2017; 23(35): 6482-6490
URL	http://www.wjgnet.com/1007-9327/full/v23/i35/6482.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i35.6482

Full Article (PDF)	WJG-23-6482.pdf
Full Article (Word)	WJG-23-6482.doc
Manuscript File	33771-Review.docx
Answering Reviewers	33771-Answering reviewers.pdf
Audio Core Tip	33771-Audio core tip.mp3
Biostatistics Review Certificate	33771-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	33771-Conflict-of-interest statement.pdf
Copyright License Agreement	33771-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	33771-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	33771-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	33771-Language certificate.pdf
Peer-review Report	33771-Peer-review(s).pdf
Scientific Misconduct Check	33771-Scientific misconduct check.pdf
Scientific Editor Work List	33771-Scientific editor work list.pdf