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Articles Published Processes
8/18/2017 1:45:25 AM | Browse: 1065 | Download: 1651
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Received |
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2017-03-01 08:20 |
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Peer-Review Started |
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2017-03-02 16:35 |
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To Make the First Decision |
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2017-03-27 11:26 |
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Return for Revision |
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2017-03-28 16:05 |
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Revised |
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2017-04-24 09:58 |
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Second Decision |
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2017-06-02 00:25 |
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Accepted by Journal Editor-in-Chief |
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2017-06-02 01:35 |
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Accepted by Executive Editor-in-Chief |
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2017-06-20 02:03 |
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Articles in Press |
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2017-06-20 02:03 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-08-14 07:59 |
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Publish the Manuscript Online |
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2017-08-18 01:45 |
ISSN |
1948-5182 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Review |
Article Title |
Innate lymphoid cells in tissue homeostasis and diseases
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Manuscript Source |
Invited Manuscript |
All Author List |
Aline Ignacio, Cristiane Naffah Souza Breda and Niels Olsen Saraiva Camara |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) |
2012/02270-2 |
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Corresponding Author |
Niels Olsen Saraiva Camara, MD, PhD, Professor, Laboratory of Transplantation Immunobiology, Institute of Biomedical Sciences, Department of Immunology, University of São Paulo, Av. Prof. Lineu Prestes, 1730, Cidade Universitária, São Paulo, SP 05508-900, Brazil. niels@icb.usp.br |
Key Words |
Innate lymphoid cells; Intestine; Liver; Homeostasis; Inflammatory diseases |
Core Tip |
Receiving approximately 70% of blood through the portal vein, the liver represents one of the most important sites of defense against invading pathogens. In addition, the liver and the intestine are important immune organs, as they are often in contact with antigens and endotoxins produced by the gut microbiota. These organs are densely populated by innate immune cells such as natural killer cells, dendritic cells, macrophages, natural killer T cells and innate lymphoid cells (ILCs), which are rapidly activated by commensal and pathogenic antigens, growth factors, cytokines and host metabolites. Recent studies have been focused on discovering the role of ILCs and how these cell populations can regulate the immune response. Our goal is to discuss innovative literature highlighting the importance of ILCs in the context of infectious disease, tissue repair, tolerance of gut microbiota and inflammatory diseases that affect the liver and intestine homeostasis. |
Publish Date |
2017-08-18 01:45 |
Citation |
Ignacio A, Breda CNS, Camara NOS. Innate lymphoid cells in tissue homeostasis and diseases. World J Hepatol 2017; 9(23): 979-989 |
URL |
http://www.wjgnet.com/1948-5182/full/v9/i23/979.htm |
DOI |
http://dx.doi.org/10.4254/wjh.v9.i23.979 |
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